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The molecular bases of the origin of complete and mosaic mutants


, : The molecular bases of the origin of complete and mosaic mutants. Genetika 21(8): 1253-1260

To study the molecular basis of the origin of complete and mosaic mutants, pBR322 plasmid with one- or two-stranded DNa damage was constructed by limited chemical modification of the plasmid DNA. Damage of one strand of DNA resulted in induction of mosaic mutants. Data were obtained indicating that complete mutations arise as a result of damage of two strands in the region of the mutagenized gene.

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Related references

Dianov G.L.; Vasyunina E.A.; Ovchinnikova L.P.; Sinitsina O.I.; Salganik R.I., 1986: The molecular basis of the origin of complete and mosaic mutants. To study the molecular basis of the origin of complete and mosaic mutants, pBR322 plasmids with damage to one or both DNA strands were constructed by limited chemical modification of plasmid DNA. Damage to one strand of DNA resulted in the inducti...

Nasim, A.; Auerbach, C., 1967: The origin of complete and mosaic mutants from mutagenic treatment of single cells. A system of color mutation in Schizosaccharomyces pombe was used for testing current theories on the production of complete (non-sectored) mutations by mutagenic treatment of uni-nucleate cells. Cells of the purple adn-7 strain were exposed to UV,...

Arman, I.P.; Devin, A.B., 1969: Interallelic complementation and the origin of complete and mosaic mutants in saccharomyces cerevisiae. Genetica (Dordrecht) 5(9): 129-135

Jenkins, J.B., 1967: The induction of mosaic and complete dumpy mutants in Drosophila melanogaster with ethyl methanesulfonate. Mutation Research 4(1): 90-92

Nasim A., 1969: Observations on the types and frequencies of complete and mosaic mutants after mutagenic treatment of schizosaccharomyces pombe. Kockova-Kratochvilova, Anna (Editor) Yeasts 622p Illus Vydavatel Stvo Slovenskej Akademie Vied: Bratislava, Czechoslovakia 343-347

Jenkins, J.B., 1969: The possible origin of EMS-induced complete dumpy mutants in Drosophila. Mutation Research 7(3): 487-489

Shevchenko, V.; Patyshev, D., 1972: Occurrence of complete and mosaic mutants in various phases of the cell cycle of Chlorella with the action of ethyleneimine and ultraviolet and gamma rays. Molekuliarnye Mekhanizmy Geneticheskikh Protsessov: 29-134

C.Auerbach, 1967: Lethal sectoring and the origin of complete mutants in Schizosaccharomyces pombe. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 4(6): 875-878

Arman, I.P.; Devin, A.B., 1969: Inter-allelic complementation and the origin of complete and mosaic mutations in Saccharomyces cerevisiae. Maps of the interallelic complementation of complete and mosaic mutations were composed for 124 ad2-mutants, previously induced by nitrous acid, and compared. "Although seven criteria were used for the comparison of complete and mosaic mutati...

Jenkins J.J., 1969: The possible origin of ethyl methane sulfonate induced complete dumpy mutants in drosophila. Mutation Research 7(3): 487-489