EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The opiate receptor and opioid peptides


Journal of Neurochemistry 28(1): 13-20
The opiate receptor and opioid peptides
The present knowledge about the opiate receptor and opioid peptides was reviewed. The opiate receptor is sculpted for a normally occurring morphine-like peptide, enkephalin, a neurotransmitter or neuromodulator of neuronal pathways in the brain that may mediate pain perception among other functions. The opiate receptor and other neurotransmitter receptors display several similarities such as differential modes of binding for agonists and antagonists, and selective influences of ions on binding which may relate to ionic mechanisms in synaptic transmission. Studies on rats and other animals were discussed.

Accession: 006728469

PMID: 188984

DOI: 10.1111/j.1471-4159.1977.tb07703.x

Download PDF Full Text: The opiate receptor and opioid peptides



Related references

Agonist-induced state of the delta-opioid receptor that discriminates between opioid peptides and opiate alkaloids. Molecular Pharmacology 44(1): 166-172, 1993

A state of the delta opioid receptor that is blind to opioid peptides yet retains high affinity for the opiate alkaloids. Van Ree, J M , Et Al (Ed ) International Congress Series, No 914 New Leads in Opioid Research; International Narcotics Research Conference, Noordwijkerhout, Netherlands, July 8-13, Xxvii+391p Elsevier Science Publishers B V (Biomedical Division): Amsterdam, Netherlands; (Dist in The Usa And Canada By Elsevier Science Publishing Co , Inc : New York, New York) Illus 159-161, 1990

Opioid peptides and the opiate receptor. Ganong, William F And Luciano Martini (Ed ) Frontiers in Neuroendocrinology, Vol 5 X+399p Illus Raven Press: New York, N Y , Usa Isbn 0-89004-1350 289-328, 1978

The opiates, opioid peptides (endorphins), and the opiate receptor. Texas Medicine 75(9): 41-45, 1979

Opiate receptor binding affected differentially by opiates and opioid peptides. European Journal of Pharmacology 55(1): 11-18, 1979

Presence in neuroblastoma cells of a mu 3 receptor with selectivity for opiate alkaloids but without affinity for opioid peptides. Brain Research 667(2): 229-237, 1994

Participation of mu opiate and delta opiate receptors in the realization of vegetative responses to opioid peptides. Byulleten' Eksperimental'noi Biologii i Meditsiny 101(1): 60-63, 1986

N-methyl-D-aspartic acid (NMDA) receptor antagonist MK-801 blocks non-opioid stress-induced analgesia. I. Comparison of opiate receptor-deficient and opiate receptor-rich strains of mice. Brain Research 551(1-2): 293-296, 1991

Chronic exposure to antibodies directed against anti-opiate peptides alter delta-opioid receptor levels. Peptides 20(12): 1419-1424, 2000

Heterogeneous sensitivity of cultured dorsal root ganglion neurons to opioid peptides selective for mu opiate and delta opiate receptors. Nature (London) 299(5885): 730-733, 1982