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The preservation of ovarian function in young women undergoing pelvic radiation therapy

Gynecologic Oncology 18(3): 373-379

The preservation of ovarian function in young women undergoing pelvic radiation therapy

Because cervical carcinoma rarely metastasizes to the ovaries, it became logical to preserve ovarian function by the method of lateral ovarian transposition as part of the management of young women with this disease. This technique prevents castration should subsequent radiation therapy be planned or become necessary. Forty patients with carcinoma of the cervix or vagina underwent unilateral or bilateral ovarian transposition. Eighteen patients received radiation therapy. Of these, 16 had gonadotropin measurements, only 6 (37%) had levels elevated to the postmenopausal range. If patients whose ovaries were not shielded or who received paraaortic radiotherapy are excluded, then only 2 (17%) had elevated gonadotropin values. If properly performed, lateral ovarian transposition and ovarian shielding will apparently protect ovarian function in patients receiving pelvic radiotherapy.

Accession: 006740019

PMID: 6430756

DOI: 10.1016/0090-8258(84)90049-0

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