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The preserved tympano ossicular homo graft

, : The preserved tympano ossicular homo graft. Journal of Laryngology and Otology 90(10): 907-914

The biological aspects of the use of homografts of the sound-conducting mechanism were the subject of a large series of experimental studies in rats. Preservation in formaldehyde apparently abolished the bone induction principle, which was preserved to a certain extent after alcohol and Cialit storage. Signs of an immunological reaction were found around formaldehyde-preserved grafts, at least in muscle and not in the middle ear. As yet there are no indications pointing towards an inferior clinical behavior of formaldehyde grafts compared with those preserved in alcohol or Cialit. As far as can be concluded from the clinical series, there seems to be no difference in primary take rate. Specimens removed from failed clinical cases revealed a wide variety of microscopic structures.

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Accession: 006740039

PMID: 993653

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Related references

Vasile C., 1981: Comments on the use of tympano ossicular homo grafts in tympano plastic surgery. During the last 2 decades considerable progress was made in auditory reconstructive surgery; this was the result of improvements in both instrumentation and treatment, including drugs. Of the new surgical techniques, tympano-ossicular homografts w...

Mawson S., 1970: Tympano ossicular homo grafts. Acta Oto Rhino Laryngologica Belgica: 125-131

Marquet J., 1970: Problems associated with tympano ossicular homo grafts. Acta Oto-Rhino-Laryngologica Belgica 24(1)

Marquet J., 1971: Tympano ossicular homo grafts in surgical treatment of ear agenesis preliminary report. Acta Oto-Rhino-Laryngologica Belgica 25(6): 885-897

Veldman, J.E.; Kuijpers, W., 1981: Antigenicity of tympano-ossicular homografts of the middle ear: analyses of immune response to viable and preserved grafts in animal models. Primary and secondary response transplantation experiments in allograft tympanoplasty reveal that after various preservation procedures at least part of the original histoincompatibility between donor and recipient still exists. Clinical pathologi...

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Lesinski S.G., 1977: Symposium on homo graft tympano plasty. Otolaryngologic Clinics of North America 10(3): 469-616

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