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The preserved tympano ossicular homo graft

Journal of Laryngology and Otology 90(10): 907-914
The preserved tympano ossicular homo graft
The biological aspects of the use of homografts of the sound-conducting mechanism were the subject of a large series of experimental studies in rats. Preservation in formaldehyde apparently abolished the bone induction principle, which was preserved to a certain extent after alcohol and Cialit storage. Signs of an immunological reaction were found around formaldehyde-preserved grafts, at least in muscle and not in the middle ear. As yet there are no indications pointing towards an inferior clinical behavior of formaldehyde grafts compared with those preserved in alcohol or Cialit. As far as can be concluded from the clinical series, there seems to be no difference in primary take rate. Specimens removed from failed clinical cases revealed a wide variety of microscopic structures.

Accession: 006740039

PMID: 993653

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