+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

The pressure resistance relationships of regional resistances within the coronary circulation and the steal phenomenon

The pressure resistance relationships of regional resistances within the coronary circulation and the steal phenomenon

Basic Research in Cardiology 73(6): 607-617

The descending branch of the left coronary artery was ligated in narcotized dogs and the peripheral vascular bed embolized with microspheres. A maximal pharmacological dilatation was induced with carbocromen and dipyridamole and the pressure flow relation of the regional resistances within the coronary circulation was investigated. An increase in the aortic pressure from 100-120 mm Hg decreased the total resistance of the circumflex branch by 6%, but the precollateral resistance which represents chiefly the resistance of large coronary vessels increased by 8%. A decrease with increasing pressure was also shown by the nutritive resistance (chiefly resistance of small vessels and arterioles) and the collateral resistance (resistance of spontaneous collaterals). An increase in perfusion pressure from 70 to 90 mm Hg diminished the nutritive resistance by 13% and the collateral resistance by 17%. During an increase in aortic pressure collateral flow decreased if the relationship precollateral resistance/postcollateral resistance (R1/R4) and collateral resistance/nutritive resistance R3/R2 both increased. Collateral flow increased when the quotients R1/R4 and R3/R2 remained unchanged or decreased when aortic pressure was enhanced. Apparently not every increase in aortic pressure leads to an increase in collateral flow. A decrease in collateral flow which can produce the steal phenomenon can also develop following an increase in aortic pressure in as much as the regional resistances which influence collateral flow are changed correspondingly.

(PDF emailed within 1 workday: $29.90)

Accession: 006740070

Download citation: RISBibTeXText

PMID: 747619

Related references

Clinical importance of the coronary steal phenomenon are the coronary steal phenomenon after dipyridamole and the antianginal efficacy of isosorbide dinitrate of nifedipine related to coronary anatomy. Cohn, J N And R Rittinghausen (Ed ) International Boehringer Mannheim Symposia: Mononitrates; Montreux, Switzerland, June 14-16, 1984 Xi+320p Springer-Verlag: Berlin, West Germany; New York, N Y , Usa Illus Paper 254-264, 1985

Pharmacological alterations of coronary collateral circulation; implication to the steal-phenomenon. Pflugers Archiv 373(3): 219-224, 1978

Effect of a thromboxane a 2 synthetase inhibitor on cyclical reductions of coronary flow of canine coronary circulation possible role of prostaglandin h 2 steal phenomenon between platelet and vascular tissue. Japanese Circulation Journal 48(8): 812-813, 1984

Coronary stenosis and steal phenomenon in coronary-pulmonary fistula--assessment with stress thallium tomography after coronary angioplasty and fistulectomy. Japanese Circulation Journal 57(10): 1021-1026, 1993

The high zero-flow pressure phenomenon in coronary circulation: a simulation study. Frontiers of Medical and Biological Engineering 11(4): 335-340, 2003

Hemo dilution adaptive mechanisms in coronary and systemic circulation significance in coronary pressure flow relationships. Microvascular Research 9(2): 254, 1975

Rare case of coronary to pulmonary vein fistula with coronary steal phenomenon. World Journal of Cardiology 6(7): 682-684, 2014

Acute coronary syndrome or steal phenomenon - a case of right coronary to right ventricle fistula. Kardiologia Polska 67(3): 287-290, 2009

Coronary steal phenomenon from a coronary artery to left ventricular fistula. European Heart Journal Cardiovascular Imaging 16(2): 176-176, 2015

"Reverse steal phenomenon" in a patient with coronary artery disease and coronary-left ventricular fistula. International Journal of Cardiology 115(1): E33-E35, 2006

Studies on coronary-steal phenomenon in coronary heart disease. Verhandlungen der Deutschen Gesellschaft für Kreislaufforschung 40: 435-439, 1974

Congenital aneurysm of the left main coronary artery with fistulous communication to the right atrium and coronary 'steal' phenomenon. Cardiovascular Journal of South Africa 12(1): 48-51, 2001

Coronary-subclavian steal phenomenon late after coronary artery bypass grafting: an underappreciated cause of myocardial ischemia?. Journal of Cardiovascular Medicine 10(7): 578-580, 2009

Multiple coronary LV fistulas: demonstration of coronary steal phenomenon by stress thallium scintigraphy and exercise hemodynamics. American Heart Journal 120(1): 217-219, 1990

Critical concentrations for resistances of tubercle bacilli to tuberactinomycin-N, viomycin, capreomycin, and lividomycin in patients treated with these agents (cross-resistance-relationships among resistances to aminoglucoside-antibiotics found during chemotherapy for tuberculosis). Kekkaku 50(4-5): 123-130, 1975