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The prevalence of conduction defects and cardiac arrhythmias in progressive systemic sclerosis

, : The prevalence of conduction defects and cardiac arrhythmias in progressive systemic sclerosis. Annals of Internal Medicine 94(1): 38-40

A prospective noninvasive electrocardiographic study was done on 50 patients with progressive systemic sclerosis. Thirty-two percent had abnormalities on the resting electrocardiogram, of which the commonest were left anterior fascicular block (16%) and first-degree heart block (8%). The 24-hour ambulatory continuous tape-recorded electrocardiograms showed serious abnormalities in 62% of the patients: supraventricular tachycardias (32%), conduction disturbances (14%), coupled ventricular extrasystoles (20%), and ventricular tachycardia (10%). Intracardiac electrophysiologic data were obtained in 20 of these patients, and functional abnormalities of the sinus node, atria, and atrioventricular node were noted in seven, nine, and 10 patients, respectively. One patient had prolonged His-Purkinje conduction time. Of the 20 patients who had electrophysiologic studies, only six had entirely normal findings. These results suggest a much higher degree of cardiac involvement in progressive systemic sclerosis than previously believed. We postulate that the first-degree heart block and supraventricular tachycardias may derive from a similar pathologic process, namely, fibrous atrophy of the proximal atrioventricular node.

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Accession: 006740284

PMID: 7447221

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Lorenz, R. J., 1977: Changes in root weight and distribution in response to fertilization and harvest treatment of mixed prairie. In studies near Mandan, North Dakota, change in soil-water extraction and nutrient-removal patterns provided evidence of a change in root penetration after N application. Although N level had a strong influence on total root weight, harvest freque...

Soaud,A.A.; Saleh,M.E.; El-Tarabily,K.A.; Matsumoto,S., 2008: Effect of amending urea fertilizer with sulfur and sulfur-oxidizing bacteria strains on precision management of ammonia volatilization loss from calcareous sandy soils. The adoption of precision agriculture management requires knowledge about variability of soil responses to different treatments. Volatilization of NH<sub>3</sub> from surfaces urea-treated calcareous soils is considered one of the majo...

Dennehy, Tj; Granett, J., 1984: Monitoring decofol-resistant spider mites (Acari: Tetranychidae) in California cotton. Journal of economic entomology 77(6): 1386-1392

Patel, I.H.; Levy, R.H.; Rapport, R.L., 1977: Distribution characteristics of ethosuximide in discrete areas of rat brain. The distribution properties of ethosuximide in four regions of the rat brain--cortex, midbrain, cerebellum, and pons-medulla--were investigated following chronic intraperitoneal administration of the drug (every 12 hr for 108 hr) at four dose leve...

Teal, S.I.; Moore, G.W.; Hutchins, G.M., 1986: Development of aortic and mitral valve continuity in the human embryonic heart. The anatomic relationship of the aortic and mitral valves is a useful landmark in assessing congenital heart malformations. The atrioventricular and semilunar valve regions originate in widely separated parts of the early embryonic heart tube, and...

Shtemenko, N. I.; Pirozhkova-Patalah, I. V.; Shtemenko, A. V.; Golichenko, A. A., 2000: Investigation of influence of rhenium complexes with and organic ligands on acidic fragility of human erythrocytes. The authors showed stabilizing of rhenium binuclear cluster compounds with organic ligands on erythrocytic membranes. Estimation of functional condition of cells was studied by a chemical fragility method. Biphase type of rhenium complexes concent...

Walt, D.R., 2006: Fiber optic array biosensors. Optical fiber arrays provide a powerful substrate for creating high-density sensing systems that can address a variety of biological problems. The fiber substrate can be used, to create femtoliter wells that can be loaded with individual beads to...

Siegelman S.S.; Naidich D.P., 1984: Computed tomography of the lung and pleura. Radiology 153(SPEC ED): 190

Shih, C. N.; Marth, E. H., 1971: A procedure for rapid recovery of afla-toxins from cheese and other foods. The method involves (a) blending the sample with a mixture of chloroform, methanol and water to form a mpnophasic system, (b) adding more chloroform and water to make the system biphasic, (c) filtering to remove the food residue, (d) separating th...

Magee, R.M.; Hagan, S.; Hiscott, P.S.; Sheridan, C.M.; Carron, J.A.; McGalliard, J.; Grierson, I., 2000: Synthesis of osteonectin by human retinal pigment epithelial cells is modulated by cell density. Purpose. To determine whether human retinal pigment epithelial (HRPE) cells are able to synthesize the antiadhesive protein osteonectin, also known as secreted protein, acidic and rich in cysteine (SPARC). Additionally, because locally produced SP...