EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
EurekaMag PDF Full Text Supply ServicePDF Full Text Supply Service
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn
Follow on LinkedInFollow on Tumblr

+ Translate

The prevalence of immunological abnormalities in endemic simple goiter


, : The prevalence of immunological abnormalities in endemic simple goiter. Acta Endocrinologica 113(4): 508-513

Thyroid growth stimulating immunoglobulins microsomal antibodies and antibodies against thyroglobulin were determined in patients with simple goitre (n = 20) and controls (n = 6) living in an iodine deficient area. In addition, lymphocytic infiltration of thyroid tissue, the amount of the various lymphocyte subsets (Leu 4+, Leu3a+, and Leu 2a+ T-cells as well as B1+ B cells) in the thyroid gland, as well as the expression of the histocompatibility antigen HLA-DR on thyrocytes and intrathyroidal T-lymphocytes were examined. Goitrous patients were subdivided into two groups according to their individual iodine supply estimated by iodine excretion values, and immunological parameters were compared between patients with low (group A, iodine excretion < 70 .mu.g/24 h) and with higher (group B, iodine excretion > 100 .mu.g/24 h) iodine supply. Thyroid growth stimulating immunoglobulins and antithyroid antibodies were equally prevalent in the two patient groups, but were absent in controls. Lymphocytic infiltration of thyroid tissue was present to a comparable extent in patients of groups A and B, but to a distinctly lower degree in control persons. Intrathyroidal T-lymphocyte subsets did not differ between patients and controls. B-lymphocytes, germinal centres as well as DR+ thyrocytes were detected in goitrous patients of both groups, but never in control persons. Thus, immunological abnormalities frequently occur in patients with simple goitre and do not depend upon individual iodine supply.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006740397

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Jones W.G.; Walker K.F., 1979: Accumulation of iron manganese zinc and cadmium by the australian fresh water mussel velesunio ambiguus and its potential as a biological monitor. The accumulation of Fe, Mn, Zn and Cd by freshwater mussels in the River Murray, South Australia, and their response to changes in environmental Fe concentrations are considered. Metal loads varied markedly between individuals from the same popula...

Medina Kauwe, L. K.; Kasahara, N.; Kedes, L., 2001: 3PO, a novel nonviral gene delivery system using engineered Ad5 penton proteins. This study describes the development of 3PO, a nonviral, protein-based gene delivery vector which utilizes the highly evolved cell-binding, cell-entry and intracellular transport functions of the adenovirus serotype 5 (Ad5) capsid penton protein....

D'yachenko, N. N., 1959: Methods for determining the resistance of Tomato varieties and hybrids to virus diseases. From the All-Union Inst. for Plant Protection, Leningrad, the author reviews the following methods developed at the Gribovskaya Selection Sta. for determining virus resistance : (a) indexing at the 1st-leaf or even the cotyledon stage; (b) assessm...

Carter, FA., 1983: Sicklefin chub, Hybopsis meeki, in the Mississippi River bordering Arkansas. Arkansas Academy of Science Proceedings, 37: 80

Briles W.E., 1968: New evidence for close linkage between the a and b blood group loci of the chicken abstract. Genetics 60(1 PART 2): 164

Lazarev, V., 1976: Presence of Fomes annosus on cypress trees in Haerzegovina. Narodni sumar: 0 (4 6) 90-93

Gomez, B.; Cui, Y.; Kettner, A. J.; Peacock, D. H.; Syvitski, J. P. M., 2009: Simulating changes to the sediment transport regime of the Waipaoa River, New Zealand, driven by climate change in the twenty-first century. A one-dimensional sediment transport model (TUGS) and a climate-driven hydrological model (HydroTrend) are used to predict changes to the sediment transport regime of the Waipaoa River that may occur in response to forecast 21st Century variations...

Mcentee G.; Ryan W.; Peel A.L.G.; Rosenberg I.L.; Devlin H.B., 1988: A district general hospital experience of surgical treatment of gastric and duodenal ulcer from 1970 to 1982. Seven hundred and thirteen patients who had undergone 793 operations for peptic ulcer disease during the years 1970 to 1982 were subsequently referred to a gastric follow-up clinic. The indications for initial elective surgical treatment (514) wer...

Wali, R.; Kong, J.; Demay, M. B.; Brasitus, T. A.; Bissonnette, M.; Li, Y. C., 2001: The vitamin D receptor is not required for the rapid activation of PKC and rise in intracellular calcium induced by 1,25-dihydroxyvitamin D3 in mouse osteoblasts. Journal of Bone & Mineral Research 16(Suppl 1): S229, September

Grigor'eva, GI.; Leont'ev, VG.; Tembotov, AK., 1976: Fractional composition of hemoglobin in the small suslik of mountain and lowland populations of the northern Caucasus. Soviet J Ecol, 74: 332-337