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The prevalence of isolated atrial amyloid


, : The prevalence of isolated atrial amyloid. Journal of Pathology 153(4): 395-398

The frequency of isolated atrial amyloid (IAA), a form of 'senile' cardiac amyloidosis, was determined in younger age groups. For the detection of amyloid the Sirius red staining technique was used. IAA first appears in the fourth decade; its prevalence increases roughly linearly by 15-20 per cent with each subsequent decade, reaching 95 per cent in the 81-90 years age group. The prevalence is higher in females than in males.

Accession: 006740412

PMID: 3430237

DOI: 10.1002/path.1711530413

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Takahashi, M.; Hoshii, Y.; Kawano, H.; Gondo, T.; Yokota, T.; Okabayashi, H.; Shimada, I.; Ishihara, T., 1998: Ultrastructural evidence for the formation of amyloid fibrils within cardiomyocytes in isolated atrial amyloid. Isolated atrial amyloid (IAA) frequently affects elderly human hearts in which only the atria are involved by the deposits. Biochemical analysis has indicated that the major subunit protein of IAA is alpha-human atrial natriuretic peptide (alpha-A...

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