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The prevention of alcoholic fatty liver using dietary supplements di hydroxy acetone pyruvate and riboflavine compared to arachidonic acid in pair fed rats


, : The prevention of alcoholic fatty liver using dietary supplements di hydroxy acetone pyruvate and riboflavine compared to arachidonic acid in pair fed rats. Lipids 16(1): 43-51

Male Sprague-Dawley rats were fed for 30 days a high-fat liquid ethanol diet with dihydroxyacetone, pyruvate and riboflavine added as supplements (AMA). Plasma triglyceride (TG) levels were 6-fold greater in these rats than in those fed and alcohol with or without the supplements (AA). The liver TG content in rats fed the AMA diet was similar to that of rats fed a control diet (CA) in which alcohol was replaced with isocaloric amounts of dextrose. Livers of rats fed the AA diet had 3 times more TG than controls. Alcohol ingestion enhanced the hepatic content of cholesteryl esters (CE) and phospholipids (PL). These lipids were reduced to levels found in livers of rats fed the CA diet when dihydroxyacetone, pyruvate and riboflavine were included in the alcohol diet. The fatty acid compositions of TG, CE and PL from livers of rats fed the AMA diet were similar to those of corresponding lipids from rats fed the CA diet but differed from compositions when fed the AA diet. Regardless of the diet fed, TG had the same fatty acid composition in plasma and liver. The same was true of PL fatty acid composition. However, the fatty acid composition of CE differed between liver and plasma. The major fatty acid in liver CE was 18:1 whereas in plasma it was arachidonic acid (20:4). Reduced fatty liver was observed in an earlier study when rats were fed ad lib an ethanol diet containing 20:4. The same diet was pair-fed and fatty liver was not reduced. Dihydroxyacetone, pyruvate and riboflavine did not prevent alcohol-induced fatty liver when 20:4 was included in the AMA diet. Dietary dihydroxyacetone, pyruvate and riboflavine apparently prevent alcohol-induced fatty liver; this effect may result from increased mobilization of fat from liver.

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Tundisi T.M.; Tundisi J.; Matheus C.E., 1975: Plankton studies in a lacustrine environment part 2 spatial distribution of the zoo plankton. Ciencia e Cultura (Sao Paulo) 27(3): 269-271

Gravino, A. E.; D' Ambrosio, G.; Giglio, M.; Capraris, D. de; Tiscione, R., 1987: Use of Fungassay in the diagnosis of cutaneous mycoses in dogs. Skin and hair samples from 36 dogs, aged 1-12 years, clinically suspected of dermatomycosis, were cultured in Fungassay dermatophyte test medium and in Sabouraud's dextrose agar, and also subjected to direct microscopy. Fungassay yielded derm...

Mei-Fang, Lin; Kitahara, Marcelo Visentini; Tachikawa Hiroyuki; Fukami Hironobu; Miller, David John; Chen Chaolun Allen, 2012: Novel organization of the mitochondrial genome in the deep-sea coral, Madrepora oculata Hexacorallia, Scleractinia, Oculinidae and its taxonomic implications. Madrepora is one of the most ecologically important genera of reef-building scleractinians in the deep sea, occurring from tropical to high-latitude regions. Despite this, the taxonomic affinities and relationships within the genus Madrepora remai...

Basson, Me; Moore, Rl; O'-Rear, J; Rine, J., 1987: Identifying mutations in duplicated functions in Saccharomyces cerevisiae: recessive mutations in HMG-CoA reductase genes. Genetics 117(4): 645-655

Nakamura Michihiko, 1995: Continuous mixing of crystal mush and replenished magma in the ongoing Unzen eruption. Zoning profiles of magnetite phenocrysts in the successively effused dacite of the ongoing Unzen eruption from 1991 were analyzed to estimate the time scale of magma mixing. The dacite was formed by mixing of relatively high- and low-temperature (...

Iordache, A; Ungureanu, C; Fierlinger, U., 1978: Research on the presence of hemolysines in Pasteurella multocida. Lucrarile 4(14): 169-174

Nichols, Maynard M., 1995: Response of estuaries to storms in the Chesapeake Bay region Summary. Dyer, K R , Orth, R J Changes in fluxes in estuaries: Implications from science to management 67-70

Breslavets, L. P., 1958: Radiosensitivity of the organelles of the cell. A direct relation was noted between the sensitivity of a tissue to X-rays and its ability to multiply, and an inverse relation was noted with the extent of its differentiation. Data are given concerning the sensitivity of somatic and generative nu...

Mc Allister, J. S. V.; Rutherford, A. A., 1968: Manurial experiments with sugar beet, 1963-65. The results from 12 trials are presented dealing with the application of N, phosphate, potash and agricultural salt to sugar beet. Yields of washed roots and of sugar could be increased by the application of 50 units per acre of N. On those sites...

Stromme, Johan H., 1963: On the mechanism of disulfiram-ethanol reaction. Acta Chem Scand 17(3): 887-888