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The prevention of secondary hemorrhage after prostatectomy the value of anti fibrinolytic therapy


, : The prevention of secondary hemorrhage after prostatectomy the value of anti fibrinolytic therapy. British Journal of Urology 52(1): 26-28

This study examines the effect of antifibrinolytic therapy [tranexamic acid] on the incidence of secondary hemorrhage following endoscopic surgery. Consecutive patients [100] were allocated randomly to treatment and control groups. The incidence of secondary hemorrhage was reduced from 56% in the control group to 24% in the treatment group.

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Accession: 006740644

PMID: 7000220

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Related references

Watanabe, H.; Ishii, S.; Chigasaki, H., 1978: Fibrinolytic changes in subarachnoid hemorrhage and anti-fibrinolytic therapy--application of an anti-plasmin agent (t-AMCHA). Nihon Rinsho. Japanese Journal of Clinical Medicine 36(3): 555-562

Fortuna A.; L.T.rre E., 1970: Prevention of experimental arterial spasm from subarachnoid hemorrhage by means of an anti fibrinolytic drug. Rivista di Neurologia 40(6): 424-436

Miller, R.A.; May, M.W.; Hendry, W.F.; Whitfield, H.N.; Wickham, J.E., 1980: The prevention of secondary haemorrhage after prostatectomy: the value of antifibrinolytic therapy. This study examines the effect of antifibrinolytic therapy on the incidence of secondary haemorrhage following endoscopic surgery. One hundred consecutive patients were allocated randomly to treatment and control groups. The incidence of secondary...

Whitelaw, A.; Pople, I.; Cherian, S.; Evans, D.; Thoresen, M., 2003: Phase 1 trial of prevention of hydrocephalus after intraventricular hemorrhage in newborn infants by drainage, irrigation, and fibrinolytic therapy. Treatment of posthemorrhagic ventricular dilation in premature infants is fraught with failures and complications. We have piloted a new treatment aimed at removing intraventricular blood and the cytokines associated with hydrocephalus. Twenty-fou...

Adams H.P.Jr; Nibbelink D.W.; Torner J.C.; Sahs A.L., 1981: Anti fibrinolytic therapy in patients with aneurysmal subarachnoid hemorrhage report of the cooperative aneurysm study. Antifibrinolytic therapy (aminocaproic acid, tranexamic acid) was used in 1,114 patients who had aneurysmal subarachnoid hemorrhage (SAH). Patients were started on treatment within 1 wk after SAH was diagnosed. Therapy was discontinued 14 days aft...

Filizzolo F.; D'angelo V.A.; Donati M.B.; Porta M.; Ferrara M.; Collice M., 1977: Monitoring of anti fibrinolytic therapy in subarachnoid hemorrhage from ruptured intra cranial saccular aneurysms. Acta Neurochirurgica 36(1/2): 154-155

Panchenko V.M., 1969: Fibrinolytic hemorrhage and anti fibrinolytic preparations human. Klinicheskaya Meditsina (Moscow) 47(3): 11-17

Ishii M.; Suzuki S.; Iwabuchi T.; Julow J., 1980: Effect of anti fibrinolytic therapy on subarachnoid fibrosis in dogs after experimental subarachnoid hemorrhage. The effect of antifibrinolytic therapy on posthemorrhagic subarachnoid fibrosis was observed experimentally in dogs with scanning electron microscope. The subchronic subjects, given i.v. injections of tranexamic acid (1 mg/day) for 12 days and sac...

Sasaki, T.; Kodama, N.; Kawakami, M.; Sato, M.; Asari, J.; Sakurai, Y.; Watanabe, K.; Onuma, T.; Matsuda, T., 2000: Urokinase cisternal irrigation therapy for prevention of symptomatic vasospasm after aneurysmal subarachnoid hemorrhage: A study of urokinase concentration and the fibrinolytic system. Background and Purpose: Cisternal irrigation therapy with urokinase (UK) was performed in multiple institutions to prevent symptomatic vasospasm. The efficacy and safety of this therapy were evaluated, and the optimal concentration of UK was estim...

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