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The prevention of thrombo embolic disease by normo volemic hemo dilution

, : The prevention of thrombo embolic disease by normo volemic hemo dilution. Annales de l'Anesthesiologie Francaise 20(9): 829-832

In general surgery, routine thromboprophylaxis is strongly recommended to reduce the risk of thrombo-embolic complications. If peroperative hemodilution is used to avoid the risks of transfusions of homologous blood, dextran must be used as the diluent. Patients undergoing total hip replacement represent a very high risk group where infusion of dextran is superior to low doses of heparin, but peroperative hemodilution using dextran is more effective than infusions of dextran. Peroperative hemodilution with dextran would give similar improved results in general surgery. As with all thromboprophylactic agents, side-effects may occur. With dextran 60, anaphylactoid reactions have not been described up to the present time in patients undergoing hemodilution before operation.

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