EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The preventive effect of prednisolone on the adrenal toxicity of cadmium


, : The preventive effect of prednisolone on the adrenal toxicity of cadmium. Journal of Applied Toxicology 6(5): 377-378

The effects of a single dose of 3.3 mg/kg body weight i.p. or of a single dose of 0.2 mg/kg per os of cadmium and prednisolone on the adrenal weight and the thickness of the adrenal cortex were investigated in female mice. A significant increase was detected in the mean weight of the adrenals and the thickness of the adrenal cortex was significantly higher than the control value on days 1-3 following cadmium treatment. A dramatic decrease was observed in both adrenal weight and adrenal cortex thickness on day 4 following cadmium administration. No significant change occurred in the adrenals when prednisolone was given orally to mice following cadmium administration. This observation indicates a protective action of prednisolone on cadmium-induced adrenal toxicity.

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006740668

PMID: 3772015

DOI: 10.1002/jat.2550060513

PDF Full Text: The preventive effect of prednisolone on the adrenal toxicity of cadmium


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Preti, A., 1998: The influence of climate on suicidal behaviour in Italy. A growing number of studies report an asymmetry in the seasonal distribution of suicides, with a peak in the late spring months for both sexes. The aim of this study is to verify if the climate, apart from its seasonal change, exerts a direct infl...

Masumi, S.; Arita, M.; Morikawa, M.; Toyoda, S., 1993: Effect of dental metals on magnetic resonance imaging (MRI). The aim of this research was to examine the effects of metals used in dentistry upon magnetic resonance imaging (MRI). Ten disk-shaped samples of metals have been used in this study. Each sample has been set into a volunteer who had produced a nor...

Mogensen, J.; Hey, T.; Lambrecht, S., 2016: A Systematic Review of Phenotypic Features Associated With Cardiac Troponin I Mutations in Hereditary Cardiomyopathies. Genetic investigations have established that mutations in proteins of the contractile unit of the myocardium, known as the sarcomere, may be associated with hypertrophic cardiomyopathy (HCM), restrictive cardiomyopathy (RCM), and dilated cardiomyo...

Loveman, E.; Colquitt, J.; Rees, K., 2016: Cochrane corner: does increasing intake of dietary fibre help prevent cardiovascular disease?. Heart 102(20): 1607-1609

Carpenter A M.; Goetz F.C.; Najarian J.S.; Lazarow A., 1976: Juvenile onset diabetes quantitation of glomerular basement membrane thickness after renal transplantation. Diabetes 25(SUPPL 1): 357

Eang, R.; Girbal-Neuhauser, E.; Xu, B.; Gairin, J.Edouard., 2009: Characterization and differential expression of a newly identified phosphorylated isoform of the human 20S proteasome beta7 subunit in tumor vs. normal cell lines. The search of new pharmacological targets with original mechanism of action within the ubiquitin-proteasome pathway is still a goal to be reached in oncopharmacology. Modification by phosphorylation/dephosphorylation has been found to be involved...

Rosenfeld, R.G., 2003: Insulin-like growth factors and the basis of growth. Induction of drug metabolism was described more than 40 years ago. Progress in understanding the molecular mechanism of induction of drug-metabolizing enzymes was made recently when the important roles of the pregnane X receptor (PXR) and the cons...

Aoki, S.; Chen, Z.S.eng; Higasiyama, K.; Setiawan, A.; Akiyama, S.I.hi; Kobayashi, M., 2001: Reversing effect of agosterol A, a spongean sterol acetate, on multidrug resistance in human carcinoma cells. The effect of agosterol A, a novel polyhydroxylated sterol acetate isolated from a marine sponge, on P-glycoprotein (P-gp)-mediated multidrug-resistant cells (KB-C2) and the multidrug resistance associated protein (MRP1)-mediated multidrug-resista...

Petersen, S.R.; Alkeskjold, T.T.; Olausson, C.B.; Lægsgaard, J., 2015: Intermodal and cross-polarization four-wave mixing in large-core hybrid photonic crystal fibers. Degenerate four-wave mixing is considered in large mode area hybrid photonic crystal fibers, combining photonic bandgap guidance and index guidance. Co- and orthogonally polarized pump, signal and idler fields are considered numerically by calcula...

Meng, N.; Zhao, J.; Zhao, B.; Cheng, Y.; Wang, W.; Zhang, Y.; Zhang, S.; Miao, J., 2008: A novel butyrolactone derivative inhibited smooth muscle cell migration and proliferation and maintained endothelial cell functions through selectively affecting Na, K-ATPase activity and mitochondria membrane potential during in vitro angiogenesis. We have found that 3-benzyl-5-((2-nitrophenoxy) methyl)-dihydrofuran -2(3H)-one (3BDO), could effectively suppress human umbilical vascular endothelial cell (HUVEC) apoptosis induced by deprivation of fibroblast growth factor-2 and serum. Here, ou...