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The primary foci of linitis plastica type gastric cancer and their chronological changes

, : The primary foci of linitis plastica type gastric cancer and their chronological changes. Stomach & Intestine (Tokyo) 15(11): 1129-1136

A study was made of 7 [human] cases with linitis plastica-type gastric cancer. All the lesions were small when they were detected, but for various reasons they were followed for more than 8 mo. They were studied histologically. The lesions found at the initial examination were mostly type IIc depressed lesions, located in the area of the fundic gland or in the transitional zone. Their morphological features consisted of marginal rigidity, plateau-like elevations and elevated areas surrounding the lesions. A cancer taking the shape of linitis plastica-type probably has a tendency to infiltrate within the mucosa during an early stage of cancer development. In the course of follow-up, deep ulcers arose in 3 cases. They were reduced in size, scarred or showed recrudescence. Ulcers did not arrest the cancer growth, probably because advanced cancer was already present in the submucosa and was not influenced by the ulcers.

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