+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The primary sequence of rabbit alpha globin messenger rna

, : The primary sequence of rabbit alpha globin messenger rna. Cell 15(1): 43-54

The rabbit .alpha.-globin DNA insertion in the chimeric plasmid pHb72 (Liu et al.) was sequenced by the method of Maxam and Gilbert. The mRNA sequence beginning in the 5' untranslated region 9 nucleotides before the initiation codon and extending through the 1st 361 nucleotides of the translated region was determined. The data overlap and are in complete agreement with sequences determined by Baralle for the 5' end of the mRNA and by Proudfoot et al. for the 3' end. The sequence is in agreement with the partial complementary[c]RNA sequencing data reported previously (Paddock et al.) and with the published amino acid sequence. Save for 3 uncertain nucleotides in the 3' sequence determined by Proudfoot et al. this work marks the completion of the primary sequence of the rabbit .alpha.-globin mRNA. The high fidelity with which gene copies can be synthesized in vitro, cloned in a bacterial plasmid and maintained in the host is reaffirmed. The general features of the mRNA nucleotide sequence are discussed with particular attention given to the base composition and codon preferences observed and to comparison of this sequence with other completed mRNA gene sequences. A new computer program was used to search for the most stable base-pairing arrangement of the completed mRNA.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 006740798

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Kamuzora, H.; Ringelhann, B.; Konotey-Ahulu, F.I.; Lehmann, H.; Lorkin, P.A., 1974: The gamma-chain in a Ghanaian adult, homozygous for hereditary persistence of fetal haemoglobin. Acta Haematologica 51(3): 179-184

Moreau Benot A., 1967: Premiers resultats d'une etude palynologique du devonien de la carriere des Fours a Chaux d'Angers (Maine-et-Loire). Palynological study of 30 lower Devonian (lower Siegenian to Emsian) samples from the Fours a Chaux quarry (France) shows that only four samples contain abundant spores, two contain acritarchs, and several contain Chitinozoa. Fifty-three spore spe...

Albert Bernal, A.; Martinez Javega, J.M.; Cuquerella Cayuela, J.; Carreres Ortell, R., 1976: The behaviour of the Brasileno peach variety in conventional cold storage. Some peaches were stored in a well ventilated room with a night min. temperature of 24 deg C and a max. day temperature of 29 deg C, r.h. 55-75%. Other peaches were stored at 4 deg or 8 deg C and a r.h. of 85-90%. A temperature of 8 deg C is used...

HARRIS.R.; GRIFFIN.C.J., 1965: Glomus Tumour Of The Periodontal Tissues. Australian Dental Journal 10(1): 33-37

Tsai, T-Hsien.; Chai, H-Tan.; Sun, C-Kwan.; Yen, C-Hung.; Leu, S.; Chen, Y-Lung.; Chung, S-Ying.; Ko, S-Fat.; Chang, H-Wen.; Wu, C-Jen.; Yip, H-Kan., 2013: Obesity suppresses circulating level and function of endothelial progenitor cells and heart function. This study tested the hypothesis that obesity suppresses circulating number as well as the function of endothelial progenitor cells (EPCs) and left ventricular ejection fraction (LVEF). High fat diet (45 Kcal% fat) was given to 8-week-old C57BL/6...

Belrhali, H.; Yaremchuk, A.; Tukalo, M.; Berthet Colominas, C.; Rasmussen, B.; Bosecke, P.; Diat, O.; Cusack, S., 1995: The structural basis for seryl-adenylate and Ap-4A synthesis by seryl-tRNA synthetase. Background: Seryl-tRNA synthetase is a homodimeric class II aminoacyl-tRNA synthetase that specifically charges cognate tRNAs with serine. In the first step of this two-step reaction, Mg cntdot ATP and serine react to form the activated intermedia...

Wakeham, D.; Warr, G.G.; Atkin, R., 2013: Surfactant adsorption at the surface of mixed ionic liquids and ionic liquid water mixtures. Surface tensiometry and neutron reflectivity have been used to elucidate the structure of the adsorbed layer of nonionic surfactant tetraethylene glycol tetradecyl ether (C(14)E(4)) at the free surface of the ionic liquids ethylammonium nitrate (E...

Jundt, G.; Baumhoer, D., 2011: Hereditary bone tumors. Familial diseases leading to bone tumor formation are rare. They are mainly caused by genetic alterations of cell cycle constituent genes, such as retinoblastoma syndrome (RB1) and Li-Fraumeni syndrome (p53), of genes involved in growth-regulating...

Hell, R.; Jost, R.; Berkowitz, O.; Wirtz, M., 2002: Molecular and biochemical analysis of the enzymes of cysteine biosynthesis in the plant Arabidopsis thaliana. Among the amino acids produced by plants cysteine plays a special role as a mediator between assimilatory sulfate reduction and provision of reduced sulfur for cell metabolism. Part of this characteristic feature is the presence of cysteine synthe...

Postoway, N.; Anstee, D.J.; Wortman, M.; Garratty, G., 1988: A severe transfusion reaction associated with anti-EnaTS in a patient with an abnormal alpha-like red cell sialoglycoprotein. A 71-year-old woman (Ped) received 3 units of red cells (RBCs), compatible by the indirect antiglobulin test but strongly (4+) incompatible by direct agglutination at 37 degrees C. The next day, her plasma hemoglobin was 1252 mg percent and the di...