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The primary structure and species specificity of immunopoietins


, : The primary structure and species specificity of immunopoietins. Voprosy Meditsinskoi Khimii 32(2): 59-64

A model involving quasicyclization of protein molecules following the stepwise reactions of limited proteolysis was developed. On the basis of the model new active sites were detected in immunoglobulins of various species as well as chemical synthesis of the sites were carried out. The new group of the substances was designated as immunopoietins. The primary structure of various species immunoglobulins was analyzed and evolutional stability of the immunoprotein structure was shown.

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