EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The primary structure of cynomolgus monkey apolipoprotein a 1 deduced from the complementary dna sequence comparison to the human sequence


Gene (Amsterdam) 49(1): 103-110
The primary structure of cynomolgus monkey apolipoprotein a 1 deduced from the complementary dna sequence comparison to the human sequence
We have cloned and analyzed a cDNA containing the complete coding sequence for cynomolgus monkey apolipoprotein A-1 (apoA-1). This cDNA clone was found to share approx. 97% nucleotide sequence identity with the published human apoA-1 and encodes a protein of the same size as the human protein. Paired proline residues are present at positions 3 and 4 in the mature protein as has been reported for other primate species and the propeptide sequence is identical to the human propeptide. The amino acid content derived from the nucleotide sequence predicts a more basic protein than human apoA-1 and this was confirmed by isoelectric focusing analysis. In addition, we present evidence for two different transcriptional initiation sites for the cynomolgus monkey gene in contrast to only one for human.


Accession: 006740885



Related references

The primary structure of cynomolgus monkey apolipoprotein A-1 deduced from the cDNA sequence: comparison to the human sequence. Gene 49(1): 103-110, 1986

Purification, cloning and nucleotide sequence determination of cynomolgus monkey apolipoprotein C-II: comparison to the human sequence. Molecular and Cellular Biochemistry 90(1): 69-79, 1989

Nucleotide sequence of the cynomolgus monkey apolipoprotein e complementary dna. Nucleic Acids Research 17(4): 1778, 1989

Primary structure of human proacrosin deduced from its complementary dna sequence. Febs Letters 244(2): 296-300, 1989

Primary structure of human pre angiotensinogen deduced from the cloned complementary dna sequence. Biochemistry 23(16): 3603-3609, 1984

Primary structure of human carcinoembryonic antigen cea deduced from complementary dna sequence. Biochemical & Biophysical Research Communications 142(2): 511-518, 1987

Primary structure of human polyadp ribose synthetase as deduced from complementary dna sequence. Journal of Biological Chemistry 262(33): 15990-15998, 1987

Primary structure of human indoleamine 2 3 dioxygenase deduced from the nucleotide sequence of its complementary dna. Nucleic Acids Research 18(2): 367, 1990

Primary structure of human thyroglobulin deduced from the sequence of its 8448-base complementary DNA. European Journal of Biochemistry 165(3): 491-498, 1987

The primary structure of human bile salt activated lipase deduced from its complementary dna sequence. FASEB Journal 4(7): A1819, 1990