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The primary structure of phospho lipase a 2 ec 3.1.1.4 from porcine pancreas a reinvestigation






Biochimica et Biophysica Acta 492(2): 254-259

The primary structure of phospho lipase a 2 ec 3.1.1.4 from porcine pancreas a reinvestigation

The primary structure of porcine pancreatic phospholipase A2 (EC 3.1.1.4) was reinvestigated. A number of modifications were introduced including the addition of a 7th disulfide bridge. The structure which is presented here shows a high degree of homology with the amino acid sequence of snake venom and horse pancreas phospholipase A2.


Accession: 006740959



Related references

Puijk, W.C.; Verheij, H.M.; D.H.as, G.H., 1977: The primary structure of phospholipase A2 from porcine pancreas. A reinvestigation. The primary structure of porcine pancreatic phospholipase A2 (EC 3.1.1.4) has been reinvestigated. A number of modifications have been introduced including the addition of a 7th disulfide bridge. The structure which is presented here shows a high...

Anonymous, 1972: Structure and enzymic properties of phospho lipase a ec 3114 from porcine pancreas

Verheij, H.M.; Westerman, J.; Sternby, B.; De-Haas, G.H., 1983: The complete primary structure of phospho lipase a 2 ec 3.1.1.4 from human pancreas. The complete amino acid sequence of phospholipase A2 from human pancreas was determined. The protein consists of a single polypeptide chain of 125 amino acids and has a MW of 14,003. The chain is cross-linked by 7 disulfide bridges. The main fragm...

Dijkstra, B.W.; Renetseder, R.; Kalk, K.H.; Hol, W.G.J.; Drenth, J., 1983: Structure of porcine pancreatic phospho lipase a 2 at 2.6 angstrom resolution and comparison with bovine phospho lipase a 2. The previously published 3-dimensional structure of porcine pancreatic prophospholipase A2 at 3 .ANG. resolution was incompatible with the structures of bovine phospholipase A2 and bovine prophospholipase A2. This was unexpected because of the ver...

Bonsen P.P.M.; D.H.as G.H.; Pieterson W.A.; Van Deenen L.L.M., 1972: Studies on phospho lipase a and its zymogen from porcine pancreas part 4 the influence of chemical modification of the lecithin structure on substrate properties. Biochimica et Biophysica Acta 270(3): 364-382

Casu A.; Nanni G.; Pala V., 1968: Structure of membranes fractionated hydrolysis by enz phospho lipase a enz phospho lipase c and enz phospho lipase d of phospho lipids of sheep erythrocytes. Italian Journal of Biochemistry (English Edition) 17(5): 301-311

Anonymous, 1972: Phospho lipase a ec 3114 and its zymogen from porcine pancreas

D.H.as G.H.; Postema M.M.; Nienwenhuizen W.; Van Deenen L.L.M., 1968: Purification and properties of enz phospho lipase a and its zymogen from porcine pancreas. Bulletin de la Societe de Chimie Biologique 50(9): 1383-1384

Anonymous, 1979: The amino acid sequence of the phospho lipase a 2 ec 3114 iso enzyme from porcine pancreas

Belleville, J.; Prost, J.; Gillet, M., 1978: Effects of tri glyceride and phospho lipid rich diets on the activities of lipase and phospho lipase a from rat pancreatic juice and pancreas. Lipase and phospholipase A activities were increased in the pancreas and pancreatic juice of rats ingesting 20% phospholipid- or triglyceride-rich diets for 2 mo. The activity of lipase is higher with the triglyceride-rich diet and the phospholipa...