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Chapter 6,746

The radio allergo sorbent test for diagnosis of house dust allergy and bronchial asthma

Kirsten, D.; Lenich, R.

Allergie und Immunologie 26(1): 21-16

1980

ISSN/ISBN: 0323-4398
Accession: 006745608
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The radioallergosorbent test (RAST) was used for the in vitro diagnosis of asthma. A total of 70 investigations in 40 patients with house dust and mite allergy are reported. In 75% of the patients, RAST was positive, especially in mite allergy. Increased total Ig[immunoglobulin]E levels were correlated with positive case history and skin test results in only about 50% of the cases. After hyposensitization a better correlation was found. RAST is not an alternative, but a useful completion to the traditional methods (skin test, provocation test) used in the diagnosis of allergy, especially in mite allergy and analogous situations where provocation tests are not usually used.

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Related References

Horiuchi, Y. 1975: Clinical studies using radio allergo sorbent test correlation between the end point of scratch test and isotope count of radio allergo sorbent test clinical significance of radio allergo sorbent test and neutralization between house dust and mite antigens Japanese Journal Of Allergology: 448-454
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