EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The relationship of parietal cell, gastrin cell, and thyroid autoantibodies to the state of the gastric mucosa in a population sample






Scandinavian Journal of Gastroenterology 19(8): 1075-1080

The relationship of parietal cell, gastrin cell, and thyroid autoantibodies to the state of the gastric mucosa in a population sample

The occurrence of tissue autoantibodies in relationship to fundal and antral gastritis was examined in an Estonian rural population sample, consisting of 227 persons 15 to 69 years of age. The state of the gastric mucosa was verified with multiple biopsy specimens obtained at direct-vision gastroscopy. Isolated fundal gastritis was characterized as the presence of parietal cell (PCA) and/or thyroid antibodies. PCA was seen only in persons with normal antral mucosa. On the other hand, gastrin cell antibodies (GCA) showed no correlation to the extent of antral gastritis, being seen in normal antrum or in superficial or slight atrophic gastritis but not in moderate or severe gastritis. The findings of our present study thus strengthen the view that the occurrence of PCA is mainly limited to isolated fundal gastritis and excludes the occurrence of antral gastritis. On the other hand, an association of GCA and antral gastritis could not be established.

(PDF 0-2 workdays service: $29.90)

Accession: 006751693

PMID: 6398507



Related references

Relation of parietal cell and thyroid antibodies to the state of gastric mucosa and basal serum gastrin levels during a 6-year follow up. Clinical and Experimental Immunology 77(2): 202-205, 1989

Effects of chronic penta gastrin stimulation on parietal cell size in rat gastric mucosa. Acta Physiologica Scandinavica Supplementumal: 3, 1978

Histamine, gastrin and acetylcholine activate carbonic anhydrase IV in the parietal cell of gastric mucosa, but not CA IV in the kidney. Gastroenterology 108(4 SUPPL ): A197, 1995

Gastric parietal cell and thyroid autoantibodies in patients with Behcet's disease. Journal of the Formosan Medical Association, 2018

Hematinic deficiencies and hyperhomocysteinemia in gastric parietal cell antibody-positive or gastric and thyroid autoantibodies-negative Behcet's disease patients. Journal of the Formosan Medical Association, 2018

Circulating thyroid and gastric parietal cell autoantibodies in patients with multiple sclerosis. Italian Journal of Neurological Sciences 11(1): 31-36, 1990

Parietal cell sensitivity to penta gastrin 2 3 months after parietal cell vagotomy and 3 5 years after parietal cell vagotomy and selective gastric vagotomy. Scandinavian Journal of Gastroenterology 16(8): 1106, 1981

Gastric parietal cell and thyroid autoantibodies in Behcet's disease patients with or without atrophic glossitis. Journal of the Formosan Medical Association, 2018

The antral gastrin-producing cells in duodenal ulcer patients. A study of preoperative G-cell densities, fasting serum-gastrin, pre- and postoperative gastric acid secretion and outcome after parietal cell vagotomy. Acta Pathologica, Microbiologica, et Immunologica Scandinavica. Section A, Pathology 95(2): 99-101, 1987

Relationship between gastrin cell number, serum, antral mucosa and luminal gastrin concentration and gastric acidity in antral atrophic gastritis. Gut 31(3): 279-281, 1990