EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The venom of the wasp Campsomeris sexmaculata (F.) blocks synaptic transmission in insect CNS






Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology 87(2): 283-286

The venom of the wasp Campsomeris sexmaculata (F.) blocks synaptic transmission in insect CNS

1. The action of the venom of the wasp Campsomeris sexmaculata on the insect CNS has been studied using the cercal nerve-giant interneuron preparation of the sixth abdominal ganglion of the cockroach. 2. The venom blocks synaptic transmission either transiently (at low concentration) or for a long time (at higher concentration), and causes a permanent depolarization of the neuron with a delay. 3. The venom does not affect directly the axonal excitability.


Accession: 006792229

PMID: 2888569

DOI: 10.1016/0742-8413(87)90009-0



Related references

Piek, T.; Hue, B.; Mantel, P.; Nakajima, T.; Pelhate, M.; Yasuhara, T., 1990: Threonine6-bradykinin in the venom of the wasp Colpa interrupta (F.) presynaptically blocks nicotinic synaptic transmission in the insect CNS. 1. The venom of the solitary scoliid wasp Colpa interrupta (F.) shows a kinin-activity, when tested on a cascade of mammalian smooth muscle preparations, and, in addition, a contraction of the rat colon. 2. The venom also irreversibly blocks the n...

Piek, T.; Hue, B.; Mony, L.; Nakajima, T.; Pelhate, M.; Yasuhara, T., 1987: Block of synaptic transmission in insect CNS by toxins from the venom of the wasp Megascolia flavifrons (Fab.). 1. The effects of the venom and its fractions of Megascolia flavifrons have been studied on synaptic transmission and axonal excitability of the giant interneuron of the cockroach. 2. The venom does not affect axonal excitability, but blocks synap...

Yokota, H.; Tsubokawa, H.; Miyawaki, T.; Konno, K.; Nakayama, H.; Masuzawa, T.; Kawai, N., 2001: Modulation of synaptic transmission in hippocampal CA1 neurons by a novel neurotoxin (beta-pompilidotoxin) derived from wasp venom. We examined the effects of beta-pompilidotoxin (beta-PMTX), a neurotoxin derived from wasp venom, on synaptic transmission in the mammalian central nervous system (CNS). Using hippocampal slice preparations of rodents, we made both extracellular a...

Yokota, H.; Tsubokawa, H.; Miyawaki, T.; Konno, K.; Nakayama, H.; Masuzawa, T.; Kawai, N., 2002: Modulation of synaptic transmission in hippocampal CA1 neurons by a novel neurotoxin (beta-pompilidotoxin) derived from wasp venom. We examined the effects of beta-pompilidotoxin (beta-PMTX), a neurotoxin derived from wasp venom, on synaptic transmission in the mammalian central nervous system (CNS). Using hippocampal slice preparations of rodents, we made both extracellular a...

Piek, T.; Hue, B.; Corronc, H. le; Mantel, P.; Gobbo, M.; Rocchi, R., 1993: Presynaptic block of transmission in the insect CNS by mono- and di-galactosyl analogues of vespulakinin 1, a wasp (Paravespula maculifrons) venom neurotoxin. 1. The pharmacological properties of four synthetic analogues of the wasp neurotoxin, Vespulakinin 1, were studied using a cascade of mammalian smooth muscle preparations and the synaptic transmission from the cockroach cercal nerves to a giant in...

Piek, T.; Hue, B.; L.C.rronc, H.; Mantel, P.; Gobbo, M.; Rocchi, R., 1993: Presynaptic block of transmission in the insect cns by mono- and di-galactosyl analogues of vespulakinin 1, a wasp (Paravespula maculifrons) venom neurotoxin. 1. The pharmacological properties of four synthetic analogues of the wasp neurotoxin, Vespulakinin 1, were studied using a cascade of mammalian smooth muscle preparations and the synaptic transmission from the cockroach cercal nerves to a giant in...

Anonymous, 1988: Effects of the venom of colpa interrupta f on vertebrate smooth muscle and synaptic transmission in insect cns

Rueff, F.; Przybilla, B.; Fuchs, T.; Gall, H.; Rakoski, J.; Stolz, W.; Vieluf, D., 2001: Diagnosis and therapy of bee and wasp venom allergy: position paper of the working group Insect venom allergy of the German Society for Allergology and clinical Immunology (DGAI). Several aspects are described, including diagnosis, anamnesis, risk factors, species identification, skin tests, in vitro tests, sting provocation, symptoms, therapy (including hyposensitization [immune desensitization], indication and contraindic...

Ebo, D.G.; Hagendorens, M.M.; Schuerwegh, A.J.; Beirens, L.M-N.; Bridts, C.H.; D.C.erck, L.S.; Stevens, W.J., 2006: Flow-assisted quantification of in vitro activated basophils in the diagnosis of wasp venom allergy and follow-up of wasp venom immunotherapy. Background: Correct identification of the culprit venom is a prerequisite for specific venom immunotherapy (VIT). Despite the efficacy of VIT, issues as how to monitor treatment and when to discontinue maintenance therapy remain to be established...

Ikeno, Y.; Hirata, H.; Arima, M.; Hayashi, Y.; Watanabe, M.; Yoshida, N.; Chibana, K.; Sugiyama, K.; Fukushima, Y.; Akutsu, I.; Fukuda, T., 2013: Wasp venom allergy: effect of anti-IgE antibody on wasp venom anaphylaxis in a mouse model. Although anti-IgE antibody (Ab) therapy was recently shown to be effective in patients with bronchial asthma, no study has reported the effect of IgE therapy in the prevention of wasp venom anaphylaxis. In this study, we used a mouse model of wasp...