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Thio phosphamide induced sister chromatid exchanges in unstimulated human lymphocytes under various storage conditions

Kagramanyan, M.S.

Biologicheskii Zhurnal Armenii 34(9): 897-902

1981


Accession: 006800675

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The frequency of sister chromatid exchanges induced by thiophosphamide in the unstimulated human lymphocytes showed an increase after storing the cells for 24 h at 37.degree. C before treatment with mutagen. There was no influence of dose fractionation when the dose of mutagen was split into 2 equal fractions. The preservation of lymphocytes after mutagen treatment did not result in an increase of sister chromatid exchange level.

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