Transferable antibiotic resistance in enterobacteriaceae isolated from urinary tract infections in general practice
Poston, S.M.; Maclaren, D.M.; Thornton, V.G.
Zentralblatt für Bakteriologie Parasitenkunde Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A Medizinische Mikrobiologie und Parasitologie 240(3): 326-333
1978
ISSN/ISBN: 0300-9688
PMID: 352037
Accession: 006825396
Different coliform isolates (138) from patients with UTI [urinary tract infection] in 2 general practices in Stockport, England, showed an incidence of drug resistance of 36%; 47% of these strains transferred resistance to Escherichia coli K12. Multiple resistance, i.e., resistance to more than 2 drugs, occurred in more than a quarter of resistant isolates and sulfonamide resistance was most common. More than twice as many strains in this series (1973-74) were sulfonamide resistant compared with a previous survey (1968-70). MIC [minimal inhibitory concentration] values of R + resistant isolates were much higher with sulfonamide resistant strains than the probable urine levels during therapy, but the situation with ampicillin and tetracycline levels was variable.