Treatment of cystic ovarian disease in dairy cattle. Comparative observation of the effects of an intramuscular injection of corticosteroids and an intravenous injection of a combination of human chorionic gonadotropin and progesterone

Nakao, T.; Ono, H.

Cornell Veterinarian 67(1): 50-64


ISSN/ISBN: 0010-8901
PMID: 64331
Accession: 006835131

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Of 67 cows with cystic ovarian disease COD, of the most important causes of infertility in dairy cattle, 34 were injected i.m. with 20 mg of betamethasone or 10 mg of dexamethasone (CC) and 33 intravenously with a combination of 3000 IU of human chorionic gonadotropin and 125 mg of progesterone (HCG.cntdot.P). Pregnancy rates and intervals between treatment and conception were 32.4% and 32.1 .+-. 30.5 days, respectively, in the CC-treated cows and 30.3% and 51.6 .+-. 29.5 days in the HCG.cntdot.P-treated ones. Cows which had not responded to gonadotropin treatment showed a considerably higher pregnancy rate when treated with CC and a lower pregnancy rate when administered with HCG.cntdot.P than those which had received no treatment before. Apparently the earlier a cow was treated, the more readily she recovered. CC injection gave a satisfactory result even when performed long after calving. The estrous behavior seemed to be related with prognosis in cows with COD. In both CC-treated and HCG.cntdot. P-treated cows, the pregnancy rate was the highest in cows showing anestrus and the lowest in those exhibiting irregular estrus.