Tremorgenic toxins from penicillia part 1 colorimetric determination of tremortin a and tremortin b

Hou, C.T.; Ciegler, A.; Hesseltine, C.W., 1970: Tremorgenic toxins from penicillia part 1 colorimetric determination of tremortin a and tremortin b. Analytical Biochemistry 37(2): 422-428

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Hou C.T.; Ciegler A.; Hesseltine C.W., 1971: Tremorgenic toxins from penicillia part 2 a new tremorgenic toxin tremortin b from penicillium palitans. Canadian Journal of Microbiology 17(5): 599-603

Hou, C.T.; Ciegler, A.; Hesseltine, C.W., 1971: Tremorgenic toxins from penicillia part 3 tremortin production by penicillium sp on various agricultural commodities. Applied Microbiology 21(6): 1101-1103

Hou, C.T.; Ciegler, A.; Hesseltine, C.W., 1971: Tremorgenic toxins from penicillia. II. A new tremorgenic toxin, tremortin B, from Penicillium palitans. Tremortin B was purified by column chromatography on florisil followed by sephadex LH20 and determined to be C37H45NO5. The LD50 of A and B are 1.05 and 5.84 mg/kg mouse, respectively. A third potential tremorgen, tremortin C, was also isolated bu...

Hou, C.T.; Cieoler, A.; Hesseltine, C.W., 1971: Tremorgenic toxins from Penicillia. III. Tremortin production by Penicillium species on various agricultural commodities. Results of studies show that a low temp. (4 degrees C) favoured the accumulation of tremortin when tremortin-producing fungi (Penicillium cyclopium, P. palitans, P. crustosum and P. puberulum) were grown on various cereal grains.

Hou, C.T.; Ciegler, A.; Hesseltine, C.W., 1971: Tremorgenic toxins from penicillia. 3. Tremortin production by Penicillium species on various agricultural commodities. A low temperature (4 C) favors the accumulation of the mycotoxin tremortin when tremortin-producing molds are grown on various agricultural commodities. However, the rate of toxin formation is more rapid at a high temperature (20 C).

Hou, C.T.; Ciegler, A.; Hesseltine, C.W., 1970: Tremorgenic toxins from Penicillia. I. Colorimetric determination of tremortins A and B. A colorimetric method is described to estimate tremorgenic mycotoxins from various penicillia. The assay depends upon the formation of blue color by methanolysis of the tremorgens. Both tremortin A and tremortin B after methanolysis have the same...

Hou, C.T.; Ciegler, A.; Hesseltine, C.W., 1970: Tremorgenic toxins from Penicillin. I. Colorimetric determination of tremortins A and B. In the method described the assay depends on the formation of a blue colour by methanolysis of the tremorgens. A rapid estimation of both tremortins in Penicillium palitans was achieved by combining thin layer chromatography with the colorimetric...

Wyatt, R.D.; Hamilton, P.B.; Colwell, W.M.; Ciegler, A., 1972: The effect of tremortin A on chickens. Extracts of the toxin, prepared from Penicillium palitans, were given orally at 5-25 mg/kg body weight to chicks ranging in age from 1 day to 2 weeks. The resulting symptoms included dyspnoea, hypopnoea, ataxia, impaired righting reflex, hypersens...

Hesseltine C.W., 1971: Tremortin production by penicillium sp on various agricultural commodities. Bacteriological Proceedings:

Di-Menna, Me, 1978: Tremorgenic penicillia in ryegrass staggers outbreaks