EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Trends and results in elucidating the topochemistry of lithium in the organism


Bratislavske Lekarske Listy 74(5): 494-511
Trends and results in elucidating the topochemistry of lithium in the organism
The histotopochemistry of Li, a psychotropic drug, has remained an untreated problem in world literature until 1979. The possibilities of elucidating the histotopography of lithium salts introduced experimentally into animal tissue were studied. Li cannot be demonstrated in these tissues by purely chemical procedures. The cation of Li cannot be demonstrated either as a carbonate, fluoride or phosphate due to the intricate chemical kinetics and the histologic technical impracticability of the given reactions. The same is true for the demonstration of ammonium stearate and (complex) periodates. Although lithium salts fluoresce with 8-hydroxyquinoline, this occurrence is of little specificity. The reaction of lithium salts with methenamine and potassium ferricyanide can serve for informative histotopochemical purposes, yet the method has its drawbacks. Of the physical methods, the most promising appears to be the technically demanding approach suggested by French authors, based on neutron irradiation of tissue sections from the organs of experimental animals which had been pretreated with the enriched isotope 6Li. The alpha particles yielded by this nuclear reaction indicate the occurrence sites of Li by their traces in a suitable detector.


Accession: 006839288

PMID: 7448585



Related references

New organism for elucidating the origin of higher plant chloroplasts. Trends in Biochemical Sciences 11(6): 234, 1986

Elucidating the beneficial effect of vinylene carbonate on the electrochemistry of antimony electrodes in lithium batteries. Chemphyschem 9(17): 2610-2617, 2008

Elucidating the biochemical overwintering adaptations of Larval Cucujus clavipes puniceus, a nonmodel organism, via high throughput proteomics. Journal of Proteome Research 10(10): 4634-4646, 2011

Distribution of lithium in the organism and its elimination. Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 71(11): 1709-1712, 1971

The kinetics of lithium in human organism. Internationale Zeitschrift fuer Klinische Pharmakologie Therapie und Toxikologie 10(4): 283-291, 1974

Lithium distribution in the organism after intoxication. Psychiatria Clinica 11(2): 96-99, 1978

Kinetics of lithium in the human organism. International Journal of Clinical Pharmacology, Therapy and Toxicology 10(4): 283-291, 1974

Binding of lithium and boron to human plasma proteins II: results for a bipolar patient not on lithium therapy. Biological Trace Element Research 97(2): 117-124, 2004

Ab initio study of charge transfer between lithium and aromatic hydrocarbons. Can the results be directly transferred to the lithium-graphene interaction?. Journal of Physical Chemistry. A 118(34): 7044-7051, 2015

Recent trends in water quality in an agricultural catchment in Eastern Scotland: elucidating the roles of hydrology and land use. Environmental Science. Processes & Impacts 16(7): 1659-1675, 2014