EurekaMag.com logo
+ Translate

Trends and seasonality of antibiotic resistance of Neisseria gonorrhoeae


, : Trends and seasonality of antibiotic resistance of Neisseria gonorrhoeae. Journal of Infectious Diseases 136(5): 684-688

Over 8,400 pretreatment isolates of Neisseria gonorrhoeae collected in the United States between November 1972 and April 1975 were tested for their in vitro resistance to penicillin, ampicillin, tetracycline, and spectinomycin. Trends and seasonality of resistance were examined by use of a harmonic regression technique. During the study period, there was a significant difference among years in the mean minimal inhibitory concentrations (MICs) for each antibiotic (P less than 0.001 for penicillin, ampicillin, and tetracycline; P less 0.05 for spectinomycin), and the mean MIC for each antibiotic decreased. Resistance to tetracycline and penicillin was highest in the winter months. Seasonality of resistance, alone or as an interaction with year, approached significance (P less than 0.10) or was significant (P less than 0.05) for all four antibiotics.

(PDF same-day service: $19.90)

Accession: 006839290

PMID: 144170

DOI: 10.1093/infdis/136.5.684

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Anonymous, 1979: The National Gonorrhea Therapy Monitoring Study: II. Trends and seasonality of antibiotic resistance of Neisseria gonorrhoeae. Sexually Transmitted Diseases 6(2 Suppl): 103-111

Arreaza, L.; Salcedo, C.; Alcalá, B.; Berrón, S.; Martín, E.; Vázquez, J.A., 2002: Antibiotic resistance of Neisseria gonorrhoeae in Spain: trends over the last two decades. In vitro activities of six antimicrobial agents against 2966 strains of Neisseria gonorrhoeae, isolated in Spain between 1983 and 2001, were determined. The percentages of intermediately susceptible and resistant isolates to penicillin (MIC > o...

Yeung, K.H., 1995: Continuous surveillance of antibiotic resistant Neisseria gonorrhoeae: A tool to forewarn emerging trends in resistance. Canadian Journal of Infectious Diseases 6(6): 301-303

Olesky, M.; Zhao, S.; Rosenberg, R.L.; Nicholas, R.A., 2006: Porin-mediated antibiotic resistance in Neisseria gonorrhoeae: ion, solute, and antibiotic permeation through PIB proteins with penB mutations. Neisseria gonorrhoeae has two porins, PIA and PIB, whose genes (porA and porB, respectively) are alleles of a single por locus. We recently demonstrated that penB mutations at positions 120 and 121 in PIB, which are presumed to reside in loop 3 th...

Cohen M.S.; Chai Y.; Britigan B.E.; Svendsen T.; Adams J.; Mckenna W.R., 1988: Use of the quinone antibiotic streptonigrin to explore the iron and oxygen metabolism of neisseria gonorrhoeae mechanisms of antibiotic action and resistance. Poolman, J T , Et Al (Ed ) Gonococci And Meningococci: Epidemiology, Genetics, Immunochemistry And Pathogenesis; 5th International Pathogenic Neisseriae Conference, Noordwijkerhout, Netherlands, September 15-18, 1986 Xv+842p Kluwer Academic Publishers: Dordrecht, Netherlands; Boston, Massachusetts, Usa Illus 665-672

Maier, T.W.; Zubrzycki, L.; Coyle, M.B.; Chila, M.; Warner, P., 1975: Genetic analysis of drug resistance in neisseria gonorrhoeae product ion of increased resistance by the combination of 2 antibiotic resistance loci. Journal of Bacteriology 124(2): 834-842

Maier, T.W.; Zubrzycki, L.; Coyle, M.B.; Chila, M.; Warner, P., 1975: Genetic analysis of drug resistance in Neisseria gonorrhoeae: production of increased resistance by the combination of two antibiotic resistance loci. The studies reported here demonstrate that increased resistance of Neisseria gonorrhoeae to penicillin, tetracycline, and chloramphenicol results from the combined effect of two resistance loci. As shown by experiments with deoxyribonucleic acid f...

Sparling, P.F., 1972: Antibiotic resistance in Neisseria gonorrhoeae. Medical Clinics of North America 56(5): 1133-1144

Tapsall, J.W., 2005: Antibiotic resistance in Neisseria gonorrhoeae. The incidence of gonorrhea is increasing in developed countries and remains high elsewhere. This untenable disease burden, the complication rate in women and newborns, and the amplification of human immunodeficiency virus transmission that accompa...

van Everdingen, J.J.; van Klingeren, B.; Stolz, E., 1986: Increasing antibiotic resistance in Neisseria gonorrhoeae. Nederlands Tijdschrift Voor Geneeskunde 130(48): 2166-2168