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Trenimon biochemical physiological and genetic effects on cells and organisms

, : Trenimon biochemical physiological and genetic effects on cells and organisms. Mutation Research 65(1): 21-70

The trifunctional alkylating mutagen Trenimon interferes with the genetic material of a variety of organisms and test systems with respect to the induction of point and chromosomal mutations, sister-chromatid exchanges, recombination phenomena and phage induction. Chemical and cell physiological effects of Trenimon, aspects of cancer therapy with Trenimon and genetic effects induced by Trenimon are discussed. The available data on mutagenic effects of Trenimon are presented according to organisms or test systems. A short discussion on a possible genetic load by therapy with Trenimon in man concludes this review. DNA damage, especially the induction of cross-linkings, seems to represent the common reason for most of the described effects of Trenimon on cells and organisms.

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Accession: 006839606

PMID: 112473

DOI: 10.1016/0165-1110(79)90012-5

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Anonymous, 1955: Report on the work of this department.. This, the first report on the work of the Department, covers mainly the period from 1940 to the date of publication. It is intended to issue annual reports from that date onwards. Summaries are presented of the work carried out by sections dealing...

Nugent, J.H.A.; Purton, S.; Evans, M.C.., 2003: Oxygenic photosynthesis in algae and cyanobacteria: electron transfer in photosystems I and II. Advances in Photosynthesis and Respiration, 14: 133-156

Hayashi, H.; Kuroki, H.; Higashi, T.; Takeyama, H.; Yokoyama, N.; Okabe, H.; Nitta, H.; Beppu, T.; Takamori, H.; Baba, H., 2016: Thrombospondin-1 expression may be implicated in liver atrophic mechanism due to obstructed portal venous flow. Liver is an amazing organ that can undergo regenerative and atrophic changes inversely, depending on blood flow conditions. Although the regenerative mechanism has been extensively studied, the atrophic mechanism remains to be elucidated. To asses...

Miguel, J.M.; Boquete, L.; Ortega, S.; Cordero, C.Alén.; Barea, R.; Blanco, R., 2013: mfERG_LAB: Software for processing multifocal electroretinography signals. The multifocal electroretinography technique consists of performing sectorized light excitation of the retina and capturing the resulting evoked potential. This provides functional localized information about the state of the retinal neurons. Anal...

Marguerite A.T.scano; W.R.chard Peltier; Rosemarie Drummond, 2011: ICE-5G and ICE-6G models of postglacial relative sea-level history applied to the Holocene coral reef record of northeastern St Croix, USVI investigating the influence of rotational feedback on GIA processes at tropical latitudes. Fossil coral reefs along the northeastern coast of St Croix in the Caribbean Sea provide an 8 year record of dated and interpreted Holocene sea-level change. We herein compare this record with the predictions of models of glacio-hydro-isostatic ad...

Taatjes, D.J.; Roth, Jürgen., 2016: In focus in HCB. Histochemistry and Cell Biology 146(5): 513-514

Bar, A.; Sachs, M.; Hurwitz, S., 1980: Observations of the use of 1 alpha hydroxycholecalciferol in the prevention of bovine parturient paresis. Varying doses of 1 alpha-hydroxycholecalciferol (1 alpha-HCC) (50, 150, 250 and 350 micrograms) in propylene glycol were injected intramuscularly into 30 dry adult Israeli Friesian cows. Fourteen of these animals received a second dose; four were...

S''iakste, N.I.; Budylin, A.V., 1988: Stability of DNA-protein interactions in chromatin fractions with different sensitivity to nucleases. It was revealed by means of nucleoprotein-celite-chromatography that DNA-protein interactions in the chromatin fraction sensitive to micrococcal nuclease and DNase II are weaker that in the resistant one. The micrococcal nuclease destroys the DNA-...

Langiewicz, W.; Slupczynska-Kossobudzka, E., 2002: Organization and financing of mental health care in Poland. ORGANIZATION OF CARE: Health care is provided to patients with mental disorders by the state health care facilities as well as by social help agencies. Mental health care services are provided mostly by mental health facilities and partly by prima...

Yuregir, G.T.; Kayrin, L.; Curuk, M.A.if; Acarturk, E.; Unlukurt, I., 1995: Correlation between trace elements and lipid profiles. The aim of this study was to examine the plasma Cu, Zn, and Mg levels in three different groups (control, hyperlipidemic, and hypercholesterolemic) and to determine any correlation between these parameters and the level of triglyceride (T.G), chol...