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Treponema pallidum immune adherence test for sero diagnosis of syphilis part 1 an improved method of the treponema pallidum immune adherence test


, : Treponema pallidum immune adherence test for sero diagnosis of syphilis part 1 an improved method of the treponema pallidum immune adherence test. British Journal of Venereal Diseases 54(6): 369-373

Clinical investigations using the T. pallidum immune adherence (TPIA) test as reported by Nelson (1953) were performed only by Olansky et al in 1954. An improved method of the TPIA test is now described. The test was simple to perform and was highly specific for antitreponemal antibody. As it was possible to use heated T. pallidum as antigen, the antigen suspension could be preserved for long periods. The TPIA test for syphilis was evaluated by examining the sera from 40 healthy subjects and from 166 patients with syphilis.

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Related references

Tanaka, S.; Suzuki, T.; Numata, T.; Tsuyuki, K., 1978: Treponema pallidum immune adherence test for sero diagnosis of syphilis part 2 comparison with glass plate treponema pallidum hem agglutination and fluorescent treponemal antibody absorbed tests. Using sera from 340 patients with syphilis the T. pallidum immune adherence (TPIA) test was compared with the glass plate, T. pallidum hemagglutination (TPHA) and fluorescent treponemal antibody-absorbed (FTA-ABS) tests. The results of the TPIA te...

Tanaka, S.; Suzuki, T.; Numata, T., 1978: Treponema pallidum immune adherence test for sero diagnosis of syphilis part 3 clinical significance and evaluation of treatment. Antibody titers were measured in patients with clinical syphilis, and the effect of treatment on the results of the T. pallidum immune adherence (TPIA) test is reported. In the T. pallidum hemagglutination (TPHA) test little change in antibody tit...

Tanaka, S.; Suzuki, T.; Numata, T., 1978: Treponema pallidum immune adherence test for serodiagnosis of syphilis. 1: An improved method of the TPIA test. Clinical investigations using the Treponema pallidum immune adherence (TPIA) test as reported by Nelson (1953) were performed only by Olansky et al in 1954. In this paper an improved method of the TPIA test is described. The test was simple to per...

Boak, R.A.; Carpenter, C.M.; Miller, J.N., 1957: Treponema pallidum immune adherence (TPIA) test in diagnosis of syphilis. Journal of the American Medical Association 163(2): 112-114

Miller, J.N.; Boak, R.A.; Carpenter, C.M., 1959: A stable antigen for the Treponema pallidum immune adherence (TPIA) test for syphilis. Technical Bulletin of the Registry of Medical Technologists 29(7): 103-107

Tanaka, S.; Suzuki, T.; Numata, T., 1978: Treponema pallidum immune adherence test for serodiagnosis of syphilis. 3: Clinical significance and evaluation of treatment. Antibody titres were measured in patients with clinical syphilis, and the effect of treatment on the results of the Treponema pallidum immune adherence (TPIA) test is reported. In the Treponema pallidum haemagglutination (TPHA) test little change...

Tanaka S.; Suzuki T.; Shimada K.; Nishioka K., 1984: Low molecular weight immunoglobulin m antibody in syphilis detected by treponema pallidum immune adherence test. Sera obtained from patients with syphilis were subjected to gel filtration chromatography to estimate antibody activity in the fractions by means of T. pallidum immune adherence (TPIA) test. Antibody activity was found in IgM and IgG fractions and...

Tanaka, S.; Suzuki, T.; Shimada, K.; Nishioka, K., 1984: Low molecular weight-IgM antibody in syphilis detected by Treponema pallidum immune adherence (TPIA) test. Sera obtained from patients with syphilis were subjected to gel filtration chromatography to estimate antibody activity in the fractions by means of Treponema palludum immune adherence (TPIA) test. Antibody activity was found in IgM and IgG fracti...

Tanaka, S.; Suzuki, T.; Numata, T.; Tsuyuki, K., 1978: Treponema pallidum immune adherence test for serodiagnosis of syphilis. 2: Comparison with glass plate, TPHA, and FTA-ABS tests. Using sera from 340 patients with syphilis the Treponema pallidum immune adherence (TPIA) test was compared with the glass plate, T. pallidum haemagglutination (TPHA), and fluorescent treponemal antibody-absorbed (FTA-ABS) tests. The results of th...

Hoffman, B.; Lesinski, J., 1957: Studies on the depletion and adherence phenomenon (Treponema pallidum immune-adherence test). Dermatologische Wochenschrift 135(10): 233-239