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Treponema pallidum immune adherence test for sero diagnosis of syphilis part 2 comparison with glass plate treponema pallidum hem agglutination and fluorescent treponemal antibody absorbed tests


British Journal of Venereal Diseases 54(6): 374-379
Treponema pallidum immune adherence test for sero diagnosis of syphilis part 2 comparison with glass plate treponema pallidum hem agglutination and fluorescent treponemal antibody absorbed tests
Using sera from 340 patients with syphilis the T. pallidum immune adherence (TPIA) test was compared with the glass plate, T. pallidum hemagglutination (TPHA) and fluorescent treponemal antibody-absorbed (FTA-ABS) tests. The results of the TPIA test agreed with those of the glass plate, TPHA and FTA-ABS tests in 65, 82 and 73% of cases, respectively. In the quantitative TPIA test no significant correlation with the other tests was observed, and it is concluded that the TPIA test has highly individual characteristics. From gel filtration the particular feature of the test was its high sensitivity to the Ig[immunoglobulin]M antibody. The TPIA test appears to be suitable for estimating antibody in the early stages of the disease.


Accession: 006839627



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