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Treponema pallidum immune adherence test for sero diagnosis of syphilis part 2 comparison with glass plate treponema pallidum hem agglutination and fluorescent treponemal antibody absorbed tests


, : Treponema pallidum immune adherence test for sero diagnosis of syphilis part 2 comparison with glass plate treponema pallidum hem agglutination and fluorescent treponemal antibody absorbed tests. British Journal of Venereal Diseases 54(6): 374-379

Using sera from 340 patients with syphilis the T. pallidum immune adherence (TPIA) test was compared with the glass plate, T. pallidum hemagglutination (TPHA) and fluorescent treponemal antibody-absorbed (FTA-ABS) tests. The results of the TPIA test agreed with those of the glass plate, TPHA and FTA-ABS tests in 65, 82 and 73% of cases, respectively. In the quantitative TPIA test no significant correlation with the other tests was observed, and it is concluded that the TPIA test has highly individual characteristics. From gel filtration the particular feature of the test was its high sensitivity to the Ig[immunoglobulin]M antibody. The TPIA test appears to be suitable for estimating antibody in the early stages of the disease.

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Related references

Tanaka, S.; Suzuki, T.; Numata, T., 1978: Treponema pallidum immune adherence test for sero diagnosis of syphilis part 1 an improved method of the treponema pallidum immune adherence test. Clinical investigations using the T. pallidum immune adherence (TPIA) test as reported by Nelson (1953) were performed only by Olansky et al in 1954. An improved method of the TPIA test is now described. The test was simple to perform and was high...

Tanaka, S.; Suzuki, T.; Numata, T.; Tsuyuki, K., 1978: Treponema pallidum immune adherence test for serodiagnosis of syphilis. 2: Comparison with glass plate, TPHA, and FTA-ABS tests. Using sera from 340 patients with syphilis the Treponema pallidum immune adherence (TPIA) test was compared with the glass plate, T. pallidum haemagglutination (TPHA), and fluorescent treponemal antibody-absorbed (FTA-ABS) tests. The results of th...

Sharma S.; Ganguly N.K.; Mahajan R.C.; Chitkara N.L., 1977: Comparison of treponema pallidum hem agglutination test with rapid plasma reagin card test venereal disease research laboratory test and fluorescent treponemal antibody absorption test in diagnosis of syphilis. Indian Journal of Pathology & Microbiology 20(3): 151-155

Larsen S.A.; Hambie E.A.; Pettit D.E.; Perryman M.W.; Kraus S.J., 1981: Specificity sensitivity and reproducibility among the fluorescent treponemal antibody absorption test the micro hem agglutination assay for treponema pallidum antibodies and the hem agglutination treponemal test for syphilis. Using 920 sera, the specificity and reproducibility of the hemagglutination treponemal test for syphilis was compared with those of the fluorescent treponemal antibody-absorption test and microhemagglutination assay for T. pallidum antibodies; all...

Kim J.S.; Yang S.K.; Woo S.G.; Kim J.M.; Kim Y.T.; Yang S.G., 1977: Comparison of serological reactions of syphilis on 27 sera part 1 treponema pallidum hem agglutination and fluorescent treponemal antibody absorption and results in part. Kyungpook University Medical Journal 18(2): 299-303

Herremans, M.; Notermans, D.W.; Mommers, M.; Kortbeek, L.M., 2007: Comparison of a Treponema pallidum IgM immunoblot with a 19S fluorescent treponemal antibody absorption test for the diagnosis of congenital syphilis. We compared an in-house Treponema pallidum IgM immunoblot (IB) with a 19S fluorescent treponemal antibody absorption (IgM) test during routine use for the diagnosis of congenital syphilis (CS) in a national reference laboratory in a nonendemic se...

Tanaka, S.; Suzuki, T.; Numata, T., 1978: Treponema pallidum immune adherence test for sero diagnosis of syphilis part 3 clinical significance and evaluation of treatment. Antibody titers were measured in patients with clinical syphilis, and the effect of treatment on the results of the T. pallidum immune adherence (TPIA) test is reported. In the T. pallidum hemagglutination (TPHA) test little change in antibody tit...

Borkhardt H L., 1974: Studies on the efficiency of the treponema pallidum immobilization lysozyme test in comparison to the fluorescent treponemal antibody absorption test and the treponema pallidum immobilization standard test. Zeitschrift fuer Immunitaetsforschung Experimentelle und Klinische Immunologie 146(4): 292-299

Schneiderka P.; Vancurik J.; Weberschinke J., 1970: Importance of fluorescent treponemal antibody absorption test in the diagnosis of syphilis comparison with classical reactions and treponema pallidum immobilization antibody test. Ceskoslovenska Epidemiologie Mikrobiologie Imunologie 19(5): 225-229

Pepose J.S.; Bishop N.H.; Feigenbaum S.; Miller J.N.; Zeltzer P.M., 1980: The humoral immune response in rabbits infected with treponema pallidum comparison of antibody levels measured by the staphylococcal protein a immuno globulin g micro assay with venereal disease research laboratory fluorescent treponemal antibody absorption and treponema pallidum immobilization antibody responses during the development of acquired resistance to challenge. The ontogeny of the IgG immune response in experimental syphilis was determined by an anti-treponemal microassay (SPA-TP) in which radioiodinated staphylococcal protein A (SPA) was used. Results were compared with those obtained in the same rabbit...