EurekaMag.com logo
+ Translate

Trh in the rat cerebellum 2. uptake by cerebellar slices


, : Trh in the rat cerebellum 2. uptake by cerebellar slices. Peptides (Orlando) 2(3): 283-288

The in vitro uptake of exogenous TRH by rat cerebellar slices was investigated. TRH was taken up via a process sharing many of the properties of a high affinity transport system, i.e., saturation kinetics; high affinity kinetic constants (Km1 = 1.06 .times. 10-5 M, Km2 = 5.6 .times. 10-6 M); temperature sensitivity (Q10 = 1.48); dependency on the Na concentration in the incubation medium; and tissue/medium ratios greater than 1. After 60 min of incubation at 27.degree. C in the presence of bacitracin, the tissue/medium ratio was 5:1. Under these conditions 70% of the total label was recovered as [3H-Pro]TRH. These findings demonstrated the existence of removal mechanisms for TRH in the cerebellum and gave further support to the hypothesis that TRH plays a functional role in this extrahypothalamic brain region.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006839737

PMID: 6795609

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Malhotra, S.L.; Maity, B.K., 1973: Prevalence of rheumatic heart disease in Railway school children in India. Indian Heart Journal 25(4): 282-288

Celli, G.; Porrini, C.; Tiraferri, S., 1987: The honeybee as a pesticide warning system. In Forli province, Italy, over 20 monitoring stations, each consisting of 2 hives [of Apis mellifera] equipped with dead-bee traps, have been used since 1982 to measure pesticides in the environment. Areas were classified as high- or low-risk, and...

Liu, Y.; Wei, H.; Shan, B'en.; Liu, Q., 2004: Clinical observation on effect of dishengzhu decoction in treating vascular dementia. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi 24(9): 837-838

Anonymous, 1976: Guidelines for establishment of home health agencies. Nln Publications: 11-17

Venturin, N.; Souza, P.A. de; Macedo, R.L.G. de; Nogueira, F.D., 2005: Mineral fertilization of candeia (Eremanthus erythropappus (DC.) McLeish). This study evaluated the nutritional aspects and the effect of nutrient omission in development of candeia seedlings (Eremanthus erythropappus). The experiment, based on missing-nutrient technique, was developed in a greenhouse, using a low fertil...

Christianson, C.A.; Ing, P.S.; Smith, J.M., 1999: Data collection in the Great Plains Genetics Service Network. American Journal of Human Genetics 65(4): A212, Oct

Li, J.; Liu, B.; Wang, Z., 2015: Planning and construction of national health laboratory network. Zhonghua Liu Xing Bing Xue Za Zhi 35(4): 453-455

Levy, J.A., 1996: Infection by human immunodeficiency virus--CD4 is not enough. New England Journal of Medicine 335(20): 1528-1530

Chen, C-Ping.; Hsu, C-Yuan.; Lee, C-Chi.; Chen, W-Lin.; Chen, L-Feng.; Wang, W., 2004: Prenatal diagnosis of de novo pure partial monosomy 4p (4p15.1-->pter) in a growth-restricted fetus with a Greek warrior helmet face and unilateral facial cleft on three-dimensional ultrasound. Prenatal Diagnosis 24(11): 934-936

Dolganov, P.V.; Cluzeau, P., 2008: Influence of chirality on director configuration and droplet interaction in ferroelectric free-standing films. Droplets in smectic free-standing films interact due to elastic distortion of the c-director field and formation of topological defects. Our experiments show that chirality of the liquid-crystal medium plays a key role in the interaction between d...