+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Trh receptors in regulation of prolactin gene expression in gh cells

, : Trh receptors in regulation of prolactin gene expression in gh cells. Biochemical & Biophysical Research Communications 106(3): 811-817

Three GH cell strains (rat pituitary tumor cells in culture) which synthesize different amounts of prolactin (PRL) and which exhibit a differential response to TRH, have been utilized to study the TRH receptor-modulated regulation of PRL gene expression. Equilibrium [3H]TRH binding studies revealed that, PRL-producing (PRL+) GH4C1 and 928-9b GH substrains possess TRH specific receptors with similar affinities for the ligand. The total number of TRH receptors per cells in TRH-nonresponsive 928-9b strain is 6.5 times < that which could be detected in TRH-responsive GH4C1 cells. Epidermal growth factor (EGF) also stimulates PRL synthesis in GH4C1 cells. Unlike TRH, EGF stimulates PRL synthesis in TRH-nonresponsive 928-9b cells, suggesting that nuclear events necessary for the stimulation of PRL gene expression in 928-9b cells are operative. 5 Bromodeoxyuridine (BrdUrd) induces PRL synthesis in PRL-nonproducing (PRL-) F1BGH12C1 cells. PRL induction in BrdUd-treated cells can not be further stimulated by TRH or EGF.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 006839789

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Anonymous, 2012: Increasing diversity awareness. Chapter takes advantage of grant program to further diversity initiative. Healthcare Executive 27(2): 100, 102-100, 102

Anonymous, 1979: Congenital commissural pits -- report of a case. Fasett 14(1): 25-26

Spooren, A.A.M.G.; Evelo, C.T.A., 1997: In vitro haematotoxic effects of three methylated hydroxylamines. Hydroxylamine (HYAM, HONH-2) and some of its derivatives are known to cause erythrotoxic effects both in vitro and in vivo. Previous studies have shown that the primary in vitro effect of HYAM and O-ethyl hydroxylamine (OEH) is methaemoglobin form...

Schmid G.; Biselli M.; Wandrey C., 1988: Preparation of cellodextrins and isolation of oligomeric side components and their characterization. Cellodextrin (.beta.-1,4-glucose oligomer) mixtures are prepared by precipitation of oligomers with 1-propanol and ethanol after partial hydrolysis of cellulose with hydrochloric acid or by acetolysis of cellulose. Celloligomers (DP3-DP8) can be i...

Anonymous, 1995: Case 6/95 (Instituto do Corac-ao do Hospital das Cl-inicas-FMUSP). Arquivos Brasileiros de Cardiologia 65(6): 501-507

SILVERMAN.A.J.; COHEN.S.I.; ZUIDEMA.G.D., 1957: Psychosomatic factors in black-out. On the basis of observation of behavior and interviews, a psychosomatic factor appeared to be identified in tolerance to G-forces. Aggressive feelings appeared related to increased tolerance, while anxiety was associated with lower black-out level...

Godard, C.; Zahnd, G.R., 1971: Growth hormone and insulin in severe infantile malnutrition. 2. Plasma insulin and growth hormone during intravenous glucose tolerance test. Glucose tolerance was tested with 0.5 g/kg by vein after fasting overnight in 14 children 10.5 to 30 months old with severe malnutrition and 40 to 60% underweight for age. Six were clinically of the marasmic type and 8 of the marasmic-kwashiorkor...

Cummings, L.L.; Harnett, D.L.; Schmidt, S.M., 1973: Factor similarity of personality across private and military samples: an analysis of the Personality-Attitude Schedule. Journal of Psychology 83(2d Half): 215-226

Samokhvalova, G. V., 1933: A Study of the Character Drooping Wing in Drosophila melanogaster. Drooping wing is a recessive character in the III chromosome. It is incompletely manifested, the percentage of manifestation fluctuating about 10 per cent. and increasing with age. It is more frequent in . A reduction of temperature leads to incre...

Meyer H.; Heron I., 1975: Lymphocyte trapping in rat specificity of the trapped cells in the popliteal lymph node following injection of semi histo incompatible cells into the hind foot pad. Scandinavian Journal of Immunology 4(7): 759