EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

TRH stimulation test in normal and in thyroid disorders


, : TRH stimulation test in normal and in thyroid disorders. Journal of the Medical Association of Thailand 67(10): 553-561

The normal and abnormal responses of TSH to synthetic TRH in 71 normal Thais and in 54 patients with thyroid disorders were defined. The concentrations of serum TSH were determined by double antibody RIA [radioimmunoassay] before and after giving 200 .mu.g of TRH at 20 and 60 min. The results revealed that normal individuals responded to TRH with reproducible increments in serum TSH. The means .+-. SE of TSH response to TRH in 71 euthyroid subjects were 1.5 .+-. 0.2 mIU/l at basal level, 13.0 .+-. 0.9 mIU/l at 20 min and 9.6 .+-. 0.7 mIU/ml at 60 min. The mean maximum increments in serum TSH at 20 min were found to be 12.0 .+-. 0.9 mIU/l with a range of 7-22 mIU/l. Sex and age differences were evaluated and the results indicated that the basal TSH levels in 48 normal females and in 23 males were not different. Hyperthyroid patients (31) showed a total lack of response to TRH and very low mean values of serum TSH at 0, 20 and 60 min were 0.5 .+-. 0.1, 0.5 .+-. 0.1 and 0.4 .+-. 0.04 mIU/l, respectively. In contrast to hyperthyroidism, all patients with primary hypothyroidism had markedly elevated baseline TSH levels. These findings suggest that the TSH response to TRH should be a sensitive and effective test in the diagnosis of thyroidal dysfunction and this test may have promise in replacing or complementing the tedious thyroid-suppression test. TRH stimulation can be used as a test of pituitary-hypothalamic function with regard to TSH.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006839815

PMID: 6440942

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Spaderna, S.; Hahn, G.; Mach, M., 2004: Glycoprotein gpTRL10 of human cytomegalovirus is dispensable for virus replication in human fibroblasts. Human cytomegalovirus (HCMV) has a coding capacity for glycoproteins which by far exceeds that of other herpesviruses. Few of these proteins have been characterized. Glycoprotein gpTRL10 represents a structural component of HCMV. The protein has n...

Zedgenizov D. A.; Shiryaev A. A.; Shatsky V. S. (Shatskiy V. S); Kagi H., 2006: Water-related IR characteristics in natural fibrous diamonds. Water-related features were studied using infrared absorption spectroscopy in fibrous diamonds with micro-inclusions. Both OH-stretching and HOH-bending vibrations were observed. The lack of correlation between the intensities of HOH and OH bands...

Jin, S. G.; Cho, J., 2009: Effects on the Earths shape due to ocean mass redistributions from GRACE observations in a warming climate. Geophysical Research Abstracts 11

Ralphs M.H., 1992: Ecology control and grazing management of locoweeds in the western usa. James, L F , Et Al (Ed ) Poisonous Plants; Third International Symposium, Logan, Utah, Usa, 1988 Xv+661p Iowa State University Press: Ames, Iowa, Usa Illus Maps 528-533

Abdou N.I.; Mckenna J.M., 1969: Immunologic studies of a spontaneous syngeneic tumor host system part 1 the role of immune mechanisms in tumor transplants in the syngeneic host. International Archives of Allergy & Applied Immunology 35(1): 20-34

White, P., 1955: Improvements in or relating to ice cream. Continuous ribbons of chilled ice cream are cut into portions with a heated reciprocating knife, before passing to the freezer. Cutting at this stage gives a smoother, cleaner cut as compared with cutting after freezing.

Silva, E.; Ugarte, R.; Andrade, A.; Edwards, A. M., 1994: Riboflavin-sensitized photoprocesses of tryptophan. The photodegradation of tryptophan in oxygen saturated aqueous solution sensitized by riboflavin is accompanied by the generation of the following reactive oxygen species: 1O-2, OH., H-2O-2 and O-2.-. When parallel photodegradation experiments are...

Tsepkin, E. A., 1962: Ichthyofauna of the Ingol and Shilka Rivers and some of their biological features. Ichthyofauna of the Ingol and Shilka consisted basically of representatives of the boreal foothill complex (Hucho taimen, Brachymystax lenok, Amur Thymallus thymallus, common Phoxinus, Salvelinus sp. and Amur Cottus), the boreal plain complex (Leu...

Riekert, H. F.; Berg, J. van den, 2003: Evaluation of chemical control measures for termites in maize. Field trials were conducted from 1994/95 to 2000/01 growing seasons in South Africa, to evaluate various insecticides for preventative and corrective control of the fungus-growing termites, Microtermes sp., Odontotermes sp., and Allodontermes sp.,...

Jang, Gi-Uk; Choi, Sang-Un; Lee, Kang-Ro, 2005: Cytotoxic constituents of Rhododendron brachycarpum. From the methanol extract of Rhododendron brachycarpum four triterpenes, three phenylpropanes and a diterpene kalkaloid were isolated. Their structures were identified as glutinol (1), 3 beta-hydroxyurs-12-ene (2), beta-sitosterol (3), (E)-p-hydro...