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Trials with rafoxanide part 7 efficacy against fasciola hepatica haemonchus placei and bunostomum phlebotomum in cattle






Journal of the South African Veterinary Association 46(3): 265-267

Trials with rafoxanide part 7 efficacy against fasciola hepatica haemonchus placei and bunostomum phlebotomum in cattle

Anthelmintic efficacy studies involving 49 cattle either naturally or artificially infested with F. hepatica are described. Some of the animals were also artificially infested with H. placei and B. phlebotomum. At dosage rates of 3.75 and 5.0 mg/kg live mass, rafoxanide was 64.6 and 92.6% effective, respectively, against adult naturally acquired infestations of F. hepatica. At 7.5 and 10.0 mg/kg it was 37.9 and 55.7% effective against 42 day old liver fluke. At 7.5 mg/kg it was 100, 87.4 and 94.6% effective against mature F. hepatica, 4th stage H. placei and adult B. phlebotomum respectively.


Accession: 006840672



Related references

Snijders, A.J.; Horak, I.G., 1975: Trials with rafoxanide. 7. Efficacy against Fasciola hepatica, Haemonchus placei and Bunostomum phlebotomum in cattle. Anthelmintic efficacy studies involving 49 cattle either naturally or artificially infected with F. hepatica are described. Some of the animals were also artificially infected with H. placei and B. phlebotomum. At dosage rates of 3.75 and 5.0 mg/k...

Horak I.G.; Snijders A.J.; Louw P.J.P., 1972: Trials with rafoxanide part 5 efficacy studies against fasciola hepatica fasciola gigantica paramphistomum microbothrium and various nematodes in sheep. Journal of the South African Veterinary Association 43(4): 397-403

Snijders A.J.; Horak I.G.; Louw J.P., 1971: Trials with rafoxanide part 2 efficacy against fasciola gigantica in cattle. Journal of the South African Veterinary Medical Association 43(3): 253-257

Bauer, C.; Hermosilla, C.; Cirak, V.Y., 1996: Efficacy of closantel against Fasciola hepatica and Haemonchus contortus: field trials in cattle and sheep. Two field trials were conducted to evaluate the efficacy of closantel, given orally at a dose rate of 10 mg/kg bodyweight, against F. hepatica and benzimidazole resistant H. contortus. The first trial was performed in a cow/calf herd of Charolais...

Horak, I.G.; Snijders, A.J.; Louw, J.P., 1972: Trials with rafoxanide. 5. Efficacy studies against Fasciola hepatica, Fasciola gigantica, Paramphistomum microbothrium and various nematodes in sheep. In South Africa, Merino lambs experimentally infected with Fasciola hepatica, Gaigeria pachyscelis and Haemonchus contortus were given rafoxanide intraruminally at 7.5 mg/kg body-weight at different times after infection. Efficacy against 28, 35 a...

Roncalli, R.A.; Morini, E.G.; Mujica, R., 1971: Efficacy of rafoxanide against Fasciola hepatica in cattle in Chile. Faecal egg count and autopsy findings showed that rafoxanide at 10, 15 or 20 mg. per kg. body-weight was at least 98.1% effective against natural Fasciola hepatica infections in 25 cattle 10 to 14 months old. No side effects were seen. The epizoot...

Knapp, S.E.; Presidente, P.J., 1971: Efficacy of rafoxanide against natural Fasciola hepatica infections in cattle. Dose levels of 5.0 and 7.5 mg/kg body wt. were administered orally by stomach tube to 2 groups each of 5 steers. At P.M. examination, infected control cattle harboured on average 4.4 flukes (minimum-maximum=0-14). Flukes were not recovered from th...

Caillier, R.L., 1972: Trial of the efficacy of rafoxanide against juvenile forms of Fasciola hepatica in cattle.. Four groups of 5 cattle, 8-12 months of age, were given individually by mouth 550 metacercariae of F. hepatica. A fifth group of 5 animals served as controls. Flukes were counted P.M. 15 weeks later. The four groups were given rafoxanide at a dose...

Ueno, H.; Alvarez, J.M.; D.M.rgen, A.M.; Cabral, A.F.; Bodden, H.A., 1973: Field trials with rafoxanide, bithionol sulfoxide and niclofolan against Fasciola hepatica in cattle in the dominican republic. Rafoxanide (15 mg/kg body weight) was highly effective in reducing F. hepatica infection in cows and calves; the faecal egg count became practically negative and this persisted for 20 weeks, the period of the experiment. The drug was also effectiv...

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