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Trichinella spiralis: alterations of blood chemistry in the mouse






Experimental Parasitology 45(2): 287-297

Trichinella spiralis: alterations of blood chemistry in the mouse

Alterations in host blood chemistry during mouse trichinosis were studied. Mice infected with T. spiralis showed depressions in serum glucose, serum pyruvate, serum total cholesterol, serum bilirubin, serum alkaline phosphatase [EC 3.1.3.1] serum total proteins, serum total globulin, uric acid, albumin, and A/G [albumin/globulin] ratio below levels found in uninfected animals. The concentrations of serum lactic dehydrogenase [EC 1.1.1.27] serum glutamic-oxaloacetic transaminase [EC 2.6.1.1], and serum creatine phosphokinase [EC 2.7.3.2] in infected mice were above that of uninfected mice. Hb, packed-cell volume (hematocrit), creatinine and Ca were at similar levels in infected and uninfected mice. These changes are discussed in terms of primary pathophysiologic lesions occurring in the gut and muscles of the trichinous host.


Accession: 006840898

PMID: 680083

DOI: 10.1016/0014-4894(78)90070-x



Related references

Hulinska, D.G.im, M.M.ckinnon, B., 1985: Alterations of muscle fibres of mice experimentally infected with Trichinella pseudospiralis, Trichinella spiralis and Trichinella nativa. Trichinellosis: proceedings of the Sixth International Conference on Trichinellosis July 8-12-1984 Far Hills Inn Val Morin Quebec Canada edited by CW Kim in association with WC Campbell et al: 162

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