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Trichinella spiralis: alterations of blood chemistry in the mouse



Trichinella spiralis: alterations of blood chemistry in the mouse



Experimental Parasitology 45(2): 287-297



Alterations in host blood chemistry during mouse trichinosis were studied. Mice infected with T. spiralis showed depressions in serum glucose, serum pyruvate, serum total cholesterol, serum bilirubin, serum alkaline phosphatase [EC 3.1.3.1] serum total proteins, serum total globulin, uric acid, albumin, and A/G [albumin/globulin] ratio below levels found in uninfected animals. The concentrations of serum lactic dehydrogenase [EC 1.1.1.27] serum glutamic-oxaloacetic transaminase [EC 2.6.1.1], and serum creatine phosphokinase [EC 2.7.3.2] in infected mice were above that of uninfected mice. Hb, packed-cell volume (hematocrit), creatinine and Ca were at similar levels in infected and uninfected mice. These changes are discussed in terms of primary pathophysiologic lesions occurring in the gut and muscles of the trichinous host.

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Accession: 006840898

Download citation: RISBibTeXText

PMID: 680083

DOI: 10.1016/0014-4894(78)90070-x



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