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Ultrastructural changes in the primary focus during cobalt induced amygdaloid epilepsy in rabbit






Pakistan Journal of Zoology 9(1): 1-10

Ultrastructural changes in the primary focus during cobalt induced amygdaloid epilepsy in rabbit

The metallic Co powder was applied to the basal amygdaloid nucleus of adult male rabbits, as an epileptogenic agent. On the 7th day after Co application, the following degenerative changes were observed in the primary focus under the EM; nucleolus in some neurons was disintegrated contour of gliocyte nuclei was disturbed, the electron density of cytoplasm in some nuclei increased, myelin sheath swelled and lost its regular structure, the number of synaptic vesicles increased and the synaptic endings and matrix darkened.


Accession: 006857273



Related references

Shaikh, M.B.; Chepurnov, S.A., 1978: Some neurographic data about the excitability of mirror focus and amygdaloid neurons during cobalt epilepsy in rabbit. The metallic Co powder was chronically implanted into the basal amygdaloid nuclei and then the chemosensitive features of the neurons in the basal amygdaloid nucleus were studied during experimental epilepsy. Under the conditions of immobilization...

Chang, L.W.; Payan, H.M., 1979: Cobalt-induced epilepsy: an ultrastructural study. Metallic cobalt and aluminum rods were implanted into the cerebral cortices of rats. Almost all the animals with cobalt implantation were found to be epileptic 30 days after the operation. Tissue samples from the cerebral cortices were sampled for...

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