+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Ultrastructural localization of acth beta lipotropin and alpha endorphin and beta endorphin in the porcine anterior pituitary



Ultrastructural localization of acth beta lipotropin and alpha endorphin and beta endorphin in the porcine anterior pituitary



Cell & Tissue Research 215(1): 87-101



The peroxidase-antiperoxidase immunocytochemical technique was used to identify the ACTH/endorphin cells in the porcine pituitary at the ultrastructural level and to determine the precise subcellular localization of the pro-ACTH/endorphin fragments. The cells display different aspects: large, regular shapes with numerous and large secretory granules; small, irregular and angular shapes with small granules aligned along the periphery of the cell; and intermediate forms. The presence of .alpha.- and .beta.-endorphin not only in the same cells but also in the same secretory granules that contain ACTH and .beta.-lipotropin clearly indicates that both the precursor or its fragments and the above-mentioned peptides are stored in the same granules and released simultaneously by the corticotropic cells. The presence of follicle stimulating hormone in some corticotropic cells is also discussed.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 006858772

Download citation: RISBibTeXText


Related references

Ultrastructural localization of corticotropin, beta-lipotropin, and alpha- and beta-endorphin in the porcine anterior pituitary. Cell and Tissue Research 215(1): 87, 1981

Ultrastructural localization of immuno reactive corticotropin beta lipotropin alpha endorphin and beta endorphin in cells of the human fetal anterior pituitary. Cell & Tissue Research 204(1): 37-52, 1979

Ultrastructural localization of corticotropin, beta-lipotropin, and alpha-endorphin in the porcine anterior pituitary. Cell and tissue research15(1): 87-101, 1981

Ultrastructural localization of immunoreactive corticotropin, beta-lipotropin, alpha- and beta-endorphin in cells of the human fetal anterior pituitary. Cell and Tissue Research 204(1): 37-51, 1979

Isolation and properties of beta endorphin 1 27 n alpha acetyl beta endorphin acth gamma lipotropin and neurophysin from equine pituitary glands. International Journal of Peptide & Protein Research 18(5): 443-450, 1981

Parallel stimulation of acth beta lipotropin plus beta endorphin and alpha melanotropin release by alpha adrenergic agents in rat anterior pituitary cells in culture. Molecular & Cellular Endocrinology 22(3): 295-304, 1981

Differentiation of cells producing poly peptide hormones acth msh lipotropic hormone alpha endorphin beta endorphin growth hormone and prolactin in the fetal porcine anterior pituitary. Cell & Tissue Research 235(3): 615-622, 1984

Hypothalamic influence on differentiation of the immuno reactive acth beta lipotropin alpha endorphin and beta endorphin containing cells in adeno hypophyseal primordia of rat fetus in organ culture. Journal de Physiologie 75(1): 27-32, 1979

Molecular forms and anterior pituitary content of ACTH, beta-lipotropin, and beta-endorphin in diabetes insipidus di/di (Brattleboro) rats. Annals of the new York Academy of Sciences 394: 574-579, 1982

Isolation and properties of beta-endorphin-(1-27), N alpha-acetyl-beta-endorphin, corticotropin, gamma-lipotropin and neurophysin from equine pituitary glands. International Journal of Peptide and Protein Research 18(5): 443-450, 1981

Immuno cytological evidence for beta lipotropin alpha endorphin and beta endorphin in pituitary gland of normal and anencephalic human fetuses. Annales d'Endocrinologie 39(3): 235-236, 1978

Immuno reactive beta endorphin beta lipotropin alpha msh acth and amino terminal fragment of pro opio melanocortin in human fetal pituitary. Biology of Reproduction 24(Suppl. 1): 60A, 1981

Biosynthesis and release of beta-endorphin-, N-acetyl beta-endorphin-, beta-endorphin-(1-27)-, and N-acetyl beta-endorphin-(1-27)-like peptides by rat pituitary neurointermediate lobe: beta-endorphin is not further processed by anterior lobe. Journal of Neuroscience 1(6): 585-595, 1981

Differentiation of cells producing polypeptide hormones (ACTH, MSH, LPH, alpha - and beta -endorphin, GH and PRL) in the fetal porcine anterior pituitary. Functional differentiation of the anterior pituitary cells in the fetal pig. An ultrastructural immunocytochemical study. Cell and Tissue Research 235(3): 615-633, 1984

Differentiation of cells producing polypeptide hormones (ACTH, MSH, LPH, alpha- and beta-endorphin, GH and PRL) in the fetal porcine anterior pituitary. Cell and Tissue Research 235(3): 615-621, 1984