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Use of mouse hepatitis virus antigen in an enzyme linked immuno sorbent assay for rat coronaviruses



Use of mouse hepatitis virus antigen in an enzyme linked immuno sorbent assay for rat coronaviruses



Laboratory Animal Science 31(5 Part 1): 472-475



An enzyme-linked immunosorbent assay (ELISA) using a mouse hepatitis virus composite antigen (mouse hepatitis virus strains S, JHM, A59 and 1) was employed for detection of antibodies to rat coronaviruses in rat sera. The test was many-fold more sensitive than the conventional complement fixation test for antibody to the rat coronaviruses but it does not allow differentiation of the infecting virus.

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Accession: 006880122

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PMID: 6281553


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