Variability of iron and copper serum concentrations and values of blood and marrow hematologic determinations in acute leukemia in children

Legutko, L.

Folia Medica Cracoviensia 20(3): 389-398


ISSN/ISBN: 0015-5616
Accession: 006890977

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Serum Fe and Cu were studied in 57 children with acute lymphoblastic leukemia. Serum Fe and Cu determinations (314) were performed using atomic absorption spectrophotometry. The highest Fe (171.2 .mu.g%) and Cu (262.7 .mu.g%) values were obtained at the beginning of the disease. Efficient treatment decreased Fe and Cu concentrations to normal values. Significant serum Cu increased in hematologic remission was observed in extra-marrow disease location (163.8 .mu.g%) in remission complicating infections (147.6 .mu.g%) and in the group of children in whom the disease recurred after 1/2-2 mo. (168.8 .mu.g%).