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Vascular occlusion and infarction in sickle cell crisis and the sickle chest syndrome



Vascular occlusion and infarction in sickle cell crisis and the sickle chest syndrome



Journal of Clinical Pathology 38(6): 659-664



A young adult with homozygous sickle cell anaemia (Hb SS) suffered a fatal sickle cell crisis complicated by the sickle chest syndrome. At necropsy multiple large infarcts of the lung, bone marrow, and pituitary gland were found. The large majority of pulmonary infarcts were not associated with either gross or microscopic vaso-occlusion. These findings are discussed and correlated with past and current opinions of sickle cell crisis and the sickle chest syndrome.

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Accession: 006897046

Download citation: RISBibTeXText

PMID: 4008666

DOI: 10.1136/jcp.38.6.659


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