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Whole saliva fluoride after toothbrushing with sodium fluoride and mono fluoro phosphate dentifrices with different fluoride concentrations



Whole saliva fluoride after toothbrushing with sodium fluoride and mono fluoro phosphate dentifrices with different fluoride concentrations



Caries Research 18(3): 282-288



The effect of F compound and F concentration in dentifrices on fluoride was assessed in whole [human] saliva after ordinary toothbrushing. The dentifrices tested had the same basic composition and contained NaF: 500, 1000 or 1500 ppm F or MFP: 1000 or 1500 ppm F. Whole saliva samples were collected at different times up to 120 min after brushing with controlled amounts of dentifrice. With all dentifrices tested, total F in whole saliva remained higher than controls for > 60 min. Total F and F- levels showed a simple relationship to the F concentration in the dentifrices. The F- levels were initially significantly lower with the MFP than with comparable NaF preparations, but 10 min brushing similar F- levels were observed with the 2 compounds. With the MFP dentifrices the proportion of F- to total F increased from 4% after 0.5 min to .apprx. 65% after 10 min, indicating that MFP was subjected to rapid hydrolysis in the oral environment.

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Accession: 006918289

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