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A case of dermoid cyst with foreign body reaction



A case of dermoid cyst with foreign body reaction



Folia Ophthalmologica Japonica 40(4): 740-744



A case of dermoid cyst with typical foreign body reaction is reported. The patient, a 13 year-old male, had a subcutaneous thumbsized tumor of the right upper lid which was flexible and elastic-soft. The tumor was surgically removed and histopathologically diagnosed as dermoid cyst. The cyst wall, which was lined by squamous epithelium, possessed adnexal structures such as hair follicles and sebaceous and eccrine sweat glands. The cystic space was filled with keratinous materials. Hairs were also found. The cyst wall was partly devoid of epithelial lining; there was foreign body reaction associated with infiltration of macrophages and multinucleate giant cells. These cells phagocytized hairs and keratinous materials. Immunohistochemistry using antikeratin antibody demonstrated that the phagosomes in the multinucleate giant cells contained keratin.

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Accession: 006932332

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