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A new vinylsilane substitution reaction with glyoxylate asymmetric synthesis of alpha hydroxy beta gamma unsaturated esters



A new vinylsilane substitution reaction with glyoxylate asymmetric synthesis of alpha hydroxy beta gamma unsaturated esters



Journal of Organic Chemistry 56(14): 4337-4339



The vinylsilane substitution reaction with glyoxylate and the asymmetric version thereof are described. These new reactions provide .alpha.-hydroxy.beta.,.gamma.-unsaturated esters of biological and synthetic importance in high enantiomeric and geometric purity.

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Accession: 006955473

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DOI: 10.1021/jo00014a002


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