+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Antibodies to escherichia coli 0157 in patients with hemorrhagic colitis and hemolytic uremic syndrome



Antibodies to escherichia coli 0157 in patients with hemorrhagic colitis and hemolytic uremic syndrome



Journal of Clinical Pathology 42(9): 973-976



Twenty four sera from patients with haemolytic uraemic syndrome of haemorrhagic colitis and healthy controls were examined for antibodies to the lipopolysaccharide (LPS) of Escherichia coli 0157. Faecal specimens from these patients were also examined for Vero cytotoxin producing E coli (VTEC) by DNA probes, and for faecal Vero cytotoxin. Eight patients with faecal E coli 0157:H7 gave a strong antibody response to 0157 LPS, shown by immunoblotting and an enzyme linked immunosorbent assay. Six symptomatic patients without evidence of faecal VTEC also gave a strong antibody response to 0157 LPS. Sera from the remaining five patients and five healthy controls did not contain antibodies to E coli 0157. The results suggest that the testing of sera from patients with haemorrhagic colitis or haemolytic uraemic syndrome by ELISA or immunoblot would prove valuable in addition to the established procedures for detecting VTEC, using DNA probes and testing for faecal Vero cytotoxin.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 007025308

Download citation: RISBibTeXText


Related references

Hemolytic uremic syndrome following hemorrhagic colitis caused by verotoxin-producing Escherichia coli 0157: H7: Early signs of hemolytic uremic syndrome. Keio Journal of Medicine 45(1): 44-47, 1996

A Dna Probe to Identify Enterohemorrhagic Escherichia coli of 0157:H7 and Other Serotypes That Cause Hemorrhagic Colitis and Hemolytic Uremic Syndrome. Journal of Infectious Diseases 156(1): 175-182, 1987

Outbreak of Escherichia coli 0157:H7 hemorrhagic colitis and hemolytic uremic syndrome: Effect on use of a pediatric emergency department. Annals of Emergency Medicine 26(5): 598-603, 1995

Sporadic cases of hemolytic uremic syndrome and hemorrhagic colitis with serum IgM antibodies to lipopolysaccharides of enterohemorrhagic Escherichia coli O157. Nihon Rinsho. Japanese Journal of Clinical Medicine 55(3): 686-692, 1997

Escherichia coli O157:H7, a cause of hemorrhagic colitis and hemolytic uremic syndrome. Acta Paediatrica Japonica 33(5): 603-612, 1991

Hemorrhagic colitis and hemolytic uremic syndrome caused by Escherichia coli O157:H7. Annales de Medecine Interne 149(5): 288-290, 1998

Hemorrhagic colitis with escherichia coli 0 157 h 7 preceding adult hemolytic uremic syndrome. Archives of Internal Medicine 145(12): 2215-2217, 1985

Characterization of shiga like toxin genes in escherichia coli strains from patients with hemorrhagic colitis hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Abstracts of the General Meeting of the American Society for Microbiology 92: 132, 1992

EAE-negative verotoxin-producing Escherichia coli associated with hemolytic uremic syndrome and hemorrhagic colitis. Karmali, M A, Goglio, A G International Congress Series; Recent advances in verocytotoxin producing Escherichia coli infections 265-268, 1994

A case of hemolytic uremic syndrome with hemorrhagic colitis due to Escherichia coli O111 infection. Korean Journal of Gastroenterology 45(5): 365-368, 2005

Vero cytotoxin producing escherichia coli in hemorrhagic colitis and hemolytic uremic syndrome. Journal of Medical Microbiology 27(3): III, 1988

Inflammatory mediators in Escherichia coli O157:H7 hemorrhagic colitis and hemolytic-uremic syndrome. Pediatric Infectious Disease Journal 17(10): 899-904, 1998

Hemorrhagic colitis caused by Escherichia coli preceding hemolytic-uremic syndrome: radiologic features. Ajr. American Journal of Roentgenology 158(3): 551-552, 1992

The role of Shiga-toxin-producing Escherichia coli in hemorrhagic colitis and hemolytic uremic syndrome. Seminars in Pediatric Infectious Diseases 15(4): 260-265, 2004

Humoral immune response to Escherichia coli 0157 lipopolysaccharide in hemolytic uremic syndrome patients and healthy subjects. Abstracts of the General Meeting of the American Society for Microbiology 95: 312, 1995