Continuous monitoring of mixed venous blood oxygen saturation in patients with congestive heart failure

Sato, M.

Journal of the Iwate Medical Association 42(5): 651-660


Accession: 007156275

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Mixed venous blood oxygen saturation (S.hivin.vO2), arterial blood oxygen saturation (SaO2), pulmonary capillary wedge pressure (PCW), cardiac index (CI), hemoglobin concentration (Hb) were measured in 24 patients with acute congestive heart failure (CHF). In order to analyze the cause of the change in S.hivin.vO2 in their early stages, arterial oxygen content (CaO2), mixed venous oxygen content (C.hivin.vO2), oxygen extraction ratio (OER), arterio-venous oxygen content difference (A-VO2difference), oxygen delivery (.ovrhdot.DO2), oxygen consumption (.ovrhdot.VO2) were calculated from the data mentioned above. Two to four days later, the same measurements were carried out again on the same patients. Retrospectively, patients were divided into two: survival group (clinically improved patients, 19 cases) and non-survival group (died during clinical course, 5 cases). In early stages, there were no significant differences in above parameters except .ovrhdot.DO2, which was lower in non-survival group. In the survival group, CI, S.hivin.vO2, SaO2 and .ovrhdot.DO2 were significantly increased, while PCW, A-VO2 difference and OER were decreased as CHF was clinically improved. .ovrhdot.VO2 and CaO2 showed no significant changes, however. In the non-survival group, S.ovrhdot.vO2, CI, .ovrhdot.DO2 and PCW tended to decrease, while OER was increased significantly. In conclusion, monitoring of S.hivin.vO2 is very useful for evaluating the proper treatment and prognosis in the patients with CHF.