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Cortisol response to corticotropin and survival in septic shock

Cortisol response to corticotropin and survival in septic shock

Lancet 337(8741): 582-583

Corticotropin stimulation tests were used to assess adrenocortical function in 32 patients with septic shock. 13 patients had a poor cortisol response (rise < 250 nmol/l) to corticotropin, all of whom died. However, there were only 6 deaths among the 19 patients with adequate responses (p < 0.001). These results suggest that some patients with septic shock may have relative adrenocortical insufficiency.

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Accession: 007165388

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PMID: 1671944

DOI: 10.1016/0140-6736(91)91641-7

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