+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Cortisol secretion in adolescents with major depressive disorder



Cortisol secretion in adolescents with major depressive disorder



Acta Psychiatrica Scandinavica 80(1): 18-26



Plasma cortisol concentrations were determined every 20 min for 24 h, in a nonstressful environment, among 48 rigorously assessed, mostly outpatient, drug-free adolescent subjects during an episode of major depression (MDD) and among 40 normal adolescent subjects. There were no significant differences in the 24-h mean, peak, or nadir, or the time of the nocturnal rise, in plasma cortisol in the 2 groups. Analyses of different subgroups of MDD adolescents according to suicidality, severity of depression, separation anxiety, psychotic subtype, endogenicity, duration of episode, and sex also revealed no significant group differences. Only one adolescent (with MDD) was identified clearly as a hypersecretor of cortisol. These results indicate that abnormalities of spontaneous cortisol secretion are an unusual finding among adolescents with major depression when studied in a nonstressful environment.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 007165392

Download citation: RISBibTeXText

PMID: 2763857


Related references

Process irregularity of cortisol and adrenocorticotropin secretion in men with major depressive disorder. Psychoneuroendocrinology 29(9): 1129-1137, 2004

Cortisol secretion in prepubertal children with major depressive disorder. Episode and recovery. Archives of General Psychiatry 46(9): 801-809, 1989

Cortisol, the cortisol-dehydroepiandrosterone ratio, and pro-inflammatory cytokines in patients with current major depressive disorder comorbid with borderline personality disorder. Biological Psychiatry 59(7): 667-671, 2005

Growth hormone secretion in children and adolescents at high risk for major depressive disorder. Archives of General Psychiatry 57(9): 867-872, 2000

Depressive rumination alters cortisol decline in Major Depressive Disorder. Biological Psychology 100: 50-55, 2015

Delta sleep inducing peptide response to human corticotropin releasing hormone chr in major depressive disorder comparison with crh induced corticotropin and cortisol secretion. Biological Psychiatry 24(2): 162-172, 1988

Effects of cortisol on cognition in major depressive disorder, posttraumatic stress disorder and borderline personality disorder - 2014 Curt Richter Award Winner. Psychoneuroendocrinology 51: 282-295, 2015

Major depressive disorder, generalised anxiety disorder, and their comorbidity: associations with cortisol in the Vietnam Experience Study. Psychoneuroendocrinology 36(5): 682-690, 2011

Add-on high frequency deep transcranial magnetic stimulation (dTMS) to bilateral prefrontal cortex in depressive episodes of patients with major depressive disorder, bipolar disorder I, and major depressive with alcohol use disorders. Neuroscience Letters 671: 128-132, 2018

Clinical characteristics of depressive symptoms in children and adolescents with major depressive disorder. Journal of Clinical Psychiatry 65(12): 1654-9; Quiz 1760-1, 2005

Fluoxetine decreased depressive symptoms in children and adolescents with non-psychotic major depressive disorder. Evidence-Based Mental Health 1(2): 49-49, 1998

Time Spent with Parents Predicts Change in Depressive Symptoms in Adolescents with Major Depressive Disorder. Journal of Abnormal Child Psychology 2019, 2019

C-reactive protein and cortisol in drug-naïve patients with short-illness-duration first episode major depressive disorder: possible role of cortisol immunomodulatory action at early stage of the disease. Journal of Affective Disorders 152-154: 534-537, 2014

Escalation to Major Depressive Disorder among adolescents with subthreshold depressive symptoms: evidence of distinct subgroups at risk. Journal of Affective Disorders 158: 133-138, 2015

Misdiagnosis of bipolar disorder in children and adolescents: a comparison with ADHD and major depressive disorder. Annals of Clinical Psychiatry 23(1): 25-29, 2011