Two novel, isomeric compounds, coumamidines .gamma.1 and .gamma.2 were isolated from fermentations of an actinomycete. The structures were elucidated spectroscopically using 2D NMR correlation experiments and mass spectral data. The coumamidines were found to be close structrual relatives of the cinodines (LL-BM 123 .gamma.1 and .gamma.2).