EurekaMag
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Detection of thoracolumbar vertebral body destruction with lateral spine radiography. Part I: Investigation in cadavers


Detection of thoracolumbar vertebral body destruction with lateral spine radiography. Part I: Investigation in cadavers



Investigative Radiology 25(5): 517-522



ISSN/ISBN: 0020-9996

PMID: 2345082

DOI: 10.1097/00004424-199005000-00008

Despite few and inconclusive studies, radiography is generally believed to be insensitive for detection of osteolytic lesions of the spine. A more detailed investigation was undertaken to study the detectability of laboratory-produced osteolytic lesions in cadaveric thoracolumbar vertebral bodies using conventional lateral radiographs. The radiographs were presented to four radiologists in two sessions over a two month period. In the first session, the films were arranged in a composite of five vertebral bodies, T11 to L3 all from the same spine, in which one contained a lesion and the other four were normal. In the second session, each vertebral body film was presented individually. Area (Az) under the receiver-operating characteristic (ROC) curve was used to measure the performances of readers. Observer detection was similar in the two formats with Az ranging from 0.67 .+-. 0.05 to 0.79 .+-. 0.04 for the composite film arrangement and 0.57 .+-. 0.08 to 0.85 .+-. 0.10 for the films of individual vertebral bodies. Lesions were grouped into three relative size categories: 18% to 25%, 26% to 40%, and 41% to 60% of transverse vertebral body diameter. The mean increase in ROC area between the small and large lesions was 0.29 (P < 0.04) for the composite films and 0.16 (P<0.05) for the individual films. In the composite study, all readers showed significant (P < 0.05) increases in lesion detection in spines reflecting large increases (P < 0.01) in bone mineral content. Mean Az for each spine was 0.57 .+-. 0.06, 0.75 .+-. 0.06 and 0.88 .+-. 0.04 while corresponding mean bone mineral equivalents were 58.8 .+-. 8.0, 89.6 .+-. 7.5, and 105.4 .+-. 9.2 mg/ml, respectively for the three spines. ROC areas for each spine correlated well (r = .99) to mean bone mineral content, but a larger number of spines must be studied to determine this relationship precisely.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 007191555

Download citation: RISBibTeXText

Related references

Detection of thoracolumbar vertebral body destruction with lateral spine radiography. Part II: Clinical investigation with computed tomography. Investigative Radiology 25(5): 523-532, 1990

An improved vertebral body replacement for the thoracolumbar spine. A biomechanical in vitro test on human lumbar vertebral bodies. Der Unfallchirurg 110(4): 327-333, 2007

Vertebral motion measured using biplanar radiography before and after Harrington rod removal for unstable thoracolumbar fractures of the spine. Spine 11(5): 452-455, 1986

Expandable vertebral body replacement in patients with thoracolumbar spine tumors. Archives of Orthopaedic and Trauma Surgery 125(10): 660-669, 2005

Osteoporotic vertebral body fractures of the thoracolumbar spine: indications and techniques of a 360°-stabilization. European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society 43(1): 27-33, 2017

Biomechanical comparison of expandable cages for vertebral body replacement in the thoracolumbar spine. Spine 29(13): 1413-1419, 2004

Osteoporotic vertebral body fractures of the thoracolumbar spine. Diagnostics and therapeutic strategies. Der Chirurg; Zeitschrift für Alle Gebiete der Operativen Medizen 83(10): 866-874, 2012

A new distractable implant for vertebral body replacement: biomechanical testing of four implants for the thoracolumbar spine. Archives of Orthopaedic and Trauma Surgery 129(10): 1375-1382, 2009

Early results after vertebral body stenting for fractures of the anterior column of the thoracolumbar spine. Injury 42(10): 1038-1042, 2011

In-vitro relationships between vertebral body density, size, and compressive strength the elderly thoracolumbar spine. Clinical Biomechanics 9(3): 180-186, 1994

Vertebral body replacement in the thoracolumbar spine via a mini-open, thoracoscopically assisted transthoracic approach. European Spine Journal: Official Publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cervical Spine Research Society 24 Suppl. 8: S949-S950, 2015

Effect of long-term axial spinal unloading on vertebral body height in adult thoracolumbar spine. European Spine Journal: Official Publication of the European Spine Society the European Spinal Deformity Society and the European Section of the Cervical Spine Research Society 17(7): 965-969, 2008

Comparison of allograft bone and titanium cages for vertebral body replacement in the thoracolumbar spine: a biomechanical study. Neurosurgery 66(6 Suppl Operative): 314-8; Discussion 318, 2010

Reliability of load-sharing classification in indications for anterior vertebral body replacement in thoracolumbar spine fractures. Rozhledy V Chirurgii: Mesicnik Ceskoslovenske Chirurgicke Spolecnosti 89(4): 223-228, 2010

Biomechanical effect of the extent of vertebral body fracture on the thoracolumbar spine with pedicle screw fixation: an in vitro study. Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia 15(3): 286-290, 2008