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Effect of age on the vaccination against newcastle disease in broiler chicks infected with gumboro disease virus



Effect of age on the vaccination against newcastle disease in broiler chicks infected with gumboro disease virus



Arquivo Brasileiro de Medicina Veterinaria e Zootecnia 42(5): 353-362



Ocular-nasal vaccination of broiler chicks with the LaSota strain of Newcastle disease (ND) as single dose was studied. The chicks had maternal antibodies anti-ND virus (NDV) and anti-Gumboro disease virus (GDV) at birth. Vaccination was done at one and ten days of age. The birds were exposed at one day of age by ocular-nasal-oral route or, alternatively, at 30 days of age by natural exposition to the A-BH-83 pathogenic strain of GDV. The birds were submitted to a challenge infection with the velogenic viscerotropic A-346 strain of NDV at 30 and 45 days of age. The results obtained permitted to conclude that, under these experimental conditions, the vaccination induced the birds to a protective specific immunoresponse against mortality due to the pathogenic strain of NDV used, independently from previous exposition to virulent GDV.

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