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Effect of flunarizine on experimentally induced facial nerve injury

Effect of flunarizine on experimentally induced facial nerve injury

Acta Oto-Laryngologica. Supplementum 446: 152-156

ISSN/ISBN: 0365-5237

PMID: 3166582

DOI: 10.3109/00016488709121858

The effect of flunarizine, a calcium antagonist, on experimentally induced facial nerve injury in guinea pigs was studied electron microscopically. In flunarizine-untreated animals, intra-axonal accumulation of cell organelles and degradation of myelin sheaths were observed. In flunarizine-treated animals, these changes were not observed, but a knob-like protrusion of myelin sheaths and a structure resembling the myelin sheath in Schwann cell cytoplasm was occasionally observed.

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Accession: 007247804

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